ArticleViruses2016
Development of an Assay for the Identification of Receptor Binding Proteins from Bacteriophages.
Article in Viruses, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 40 citations in OpenAlex.
- Polyvalent phage GSP004 recognizes O-antigen polysaccharide receptors inJournal of virology · 2025Article
- Multisite binding of bacteriophages on lipopolysaccharides inMicrobiology spectrum · 2025Article
- Graphene-Bacteriophage Hybrid Nanomaterials for Specific and Rapid Electrochemical Detection of Pathogenic Bacteria.Biosensors · 2025Review
- Engineering bacteriophages for enhanced host range and efficacy: insights from bacteriophage-bacteria interactions.Frontiers in microbiology · 2023Review
- Isolation, Purification, and Characterisation of a Phage Tail-Like Bacteriocin from the Insect Pathogenic BacteriumBiomolecules · 2022Article
- Flagellotropic Bacteriophages: Opportunities and Challenges for Antimicrobial Applications.International journal of molecular sciences · 2022Review
- Bacteriophage Tail Proteins as a Tool for Bacterial Pathogen Recognition-A Literature Review.Antibiotics (Basel, Switzerland) · 2022Review
- Isolation, characterization, molecular analysis and application of bacteriophage DW-EC to control Enterotoxigenic Escherichia coli on various foods.Scientific reports · 2022Article
- APTC-EC-2A: A Lytic Phage Targeting Multidrug ResistantMicroorganisms · 2022Article
- A Phage Receptor-Binding Protein as a Promising Tool for the Detection ofFrontiers in microbiology · 2022Article
- A novel T4- and λ-based receptor binding protein family for bacteriophage therapy host range engineering.Frontiers in microbiology · 2022Article
- Genomic characterization of bacteriophage BI-EHEC infecting strains of Enterohemorrhagic Escherichia coli.BMC research notes · 2021Article
- Article
- Article
- Specific Detection ofPathogens (Basel, Switzerland) · 2020Article
- Rapid Microscopic Detection ofMicroorganisms · 2020Article
- A Quest of Great Importance-Developing a Broad SpectrumViruses · 2019Article
- Overexpression of AmpC Promotes Bacteriophage Lysis of Ampicillin-ResistantFrontiers in microbiology · 2019Article
- Review of the nature, diversity and structure of bacteriophage receptor binding proteins that target Gram-positive bacteria.Biophysical reviews · 2018Review
- Biological roles of glycans.Glycobiology · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recently, a large number of new technologies have been developed that exploit the unique properties of bacteriophage receptor binding proteins (RBPs). These include their use in diagnostic applications that selectively capture bacteria and as therapeutics that reduce bacterial colonization in vivo. RBPs exhibit comparable, and in many cases superior, stability, receptor specificity, and affinity to other carbohydrate binding proteins such as antibodies or lectins. In order to further exploit the use of RBPs, we have developed an assay for discovering RBPs using phage genome expression libraries and protein screens to identify binding partners that recognize the host bacterium. When phage P22 was screened using this assay, Gp9 was the only RBP discovered, confirming previous predictions that this is the sole RBP encoded by this phage. We then examined the Escherichia coli O157:H7 typing phage 1 in our assay and identified a previously undescribed RBP. This general approach has the potential to assist in the identification of RBPs from other bacteriophages.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.