Evidence map›Paper›PMID 26760778›Full record

ArticleEmerging infectious diseases2016

Molecular Characterization of Invasive Streptococcus dysgalactiae subsp. equisimilis, Japan.

Takeaki Wajima, Miyuki Morozumi, Shigeo Hanada, Katsuhiko Sunaoshi, Naoko Chiba, Satoshi Iwata, Kimiko Ubukata

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 64 citations in OpenAlex.

  1. Clinical and Molecular Characteristics ofOpen forum infectious diseases · 2026
    Article
  2. Impact of comorbidity burden and skin integrity on clinical presentation and outcomes in Streptococcus dysgalactiae subspecies equisimilis bacteremia.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  3. Article
  4. Observational
  5. Genomic and patient epidemiology ofMicrobiology spectrum · 2026
    Article
  6. Article
  7. Article
  8. A Case of Necrotizing Fasciitis That Rapidly Progressed after a Minor Injury.Journal of plastic and reconstructive surgery · 2025
    Article
  9. Article
  10. Article
  11. Clinical microbiology reviews · 2024
    Review
  12. Article
  13. Clinical manifestations and biomarkers to predict mortality risk in adults with invasive Streptococcus dysgalactiae subsp. equisimilis infections.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Observational
  14. Article
  15. Article
  16. Article
  17. Diagnosis of Neurological Involvement Caused byInfection and drug resistance · 2024
    Article
  18. Incidence, seasonal pattern, and clinical manifestations of Streptococcus dysgalactiae subspecies equisimilis bacteremia; a population-based study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2023
    Article
  19. Epidemiological and Clinical Features ofPathogens (Basel, Switzerland) · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Takeaki Wajima
Miyuki Morozumi
Shigeo Hanada
Katsuhiko Sunaoshi
Naoko Chiba
Satoshi Iwata
Kimiko Ubukata
Toranomon Hospital · JPTokyo University of Pharmacy and Life Sciences · JPKeio University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We collected β-hemolytic streptococci (1,611 isolates) from patients with invasive streptococcal infections in Japan during April 2010-March 2013. Streptococcus dysgalactiae subsp. equisimilis (SDSE) was most common (n = 693); 99% of patients with SDSE infections were elderly (mean age 75 years, SD ±15 years). We aimed to clarify molecular and epidemiologic characteristics of SDSE isolates and features of patient infections. Bacteremia with no identified focus of origin and cellulitis were the most prevalent manifestations; otherwise, clinical manifestations resembled those of S. pyogenes infections. Clinical manifestations also differed by patient's age. SDSE isolates were classified into 34 emm types; stG6792 was most prevalent (27.1%), followed by stG485 and stG245. Mortality rates did not differ according to emm types. Multilocus sequence typing identified 46 sequence types and 12 novel types. Types possessing macrolide- and quinolone-resistance genes were 18.4% and 2.6%, respectively; none showed β-lactam resistance. Among aging populations, invasive SDSE infections are an increasing risk.

Indexed as

AdolescentAdultAgedAged, 80 and overAnti-Bacterial AgentsAntigens, BacterialBacterial Outer Membrane ProteinsCarrier ProteinsChildChild, PreschoolCluster AnalysisDrug Resistance, BacterialFemaleHumansInfantJapanAnti-Bacterial AgentsAntigens, BacterialBacterial Outer Membrane ProteinsCarrier Proteinsstreptococcal M proteinbacteriaemm typeJapanmultilocus sequence typingstreptococciStreptococcus dysgalactiae subsp. equisimilis

Identifiers

PMID26760778
PMCPMC4734521
OpenAlexW2400905887

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.