Evidence map›Paper›PMID 26759968›Full record

ArticleRevista de saude publica2015

Use of medicines recommended for secondary prevention of acute coronary syndrome.

Mari Ângela Gaedke, Juvenal Soares Dias da Costa, Euler Roberto Fernandes Manenti, Ruth Liane Henn, Vera Maria Vieira Paniz, Marcelo Felipe Nunes, Monique Adriane da Motta, Maria Teresa Anselmo Olinto

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Revista de saude publica, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Pathways between verbal bullying and oral conditions among school children.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Mari Ângela GaedkeUniversidade do Vale do Rio dos Sinos, São Leopoldo, RS, Brasil.
Juvenal Soares Dias da CostaUniversidade do Vale do Rio dos Sinos, São Leopoldo, RS, Brasil.
Euler Roberto Fernandes ManentiInstituto de Medicina Vascular, Hospital Mãe de Deus, Porto Alegre, RS, Brasil.
Ruth Liane HennUniversidade do Vale do Rio dos Sinos, São Leopoldo, RS, Brasil.
Vera Maria Vieira PanizUniversidade do Vale do Rio dos Sinos, São Leopoldo, RS, Brasil.
Marcelo Felipe NunesUniversidade do Vale do Rio dos Sinos, São Leopoldo, RS, Brasil.
Monique Adriane da MottaUniversidade do Vale do Rio dos Sinos, São Leopoldo, RS, Brasil.
Maria Teresa Anselmo OlintoUniversidade do Vale do Rio dos Sinos, São Leopoldo, RS, Brasil.
Universidade do Vale do Rio dos Sinos · BRHospital Mãe de Deus · BRUniversidade Federal de Ciências da Saúde de Porto Alegre · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo analyze if the demographic and socioeconomic variables, as well as percutaneous coronary intervention are associated with the use of medicines for secondary prevention of acute coronary syndrome.

methodsIn this cohort study, we included 138 patients with acute coronary syndrome, aged 30 years or more and of both sexes. The data were collected at the time of hospital discharge, and after six and twelve months. The outcome of the study was the simultaneous use of medicines recommended for secondary prevention of acute coronary syndrome: platelet antiaggregant, beta-blockers, statins and angiotensin-converting-enzyme inhibitor or angiotensin receptor blocker. The independent variables were: sex, age, education in years of attending, monthly income in tertiles and percutaneous coronary intervention. We described the prevalence of use of each group of medicines with their 95% confidence intervals, as well as the simultaneous use of the four medicines, in all analyzed periods. In the crude analysis, we verified the outcome with the independent variables for each period through the Chi-square test. The adjusted analysis was carried out using Poisson Regression.

resultsMore than a third of patients (36.2%; 95%CI 28.2;44.3) had the four medicines prescribed at the same time, at the moment of discharge. We did not observe any differences in the prevalence of use in comparison with the two follow-up periods. The most prescribed class of medicines during discharge was platelet antiaggregant (91.3%). In the crude analysis, the demographic and socioeconomic variables were not associated to the outcome in any of the three periods.

conclusionsThe prevalence of simultaneous use of medicines at discharge and in the follow-ups pointed to the under-utilization of this therapy in clinical practice. Intervention strategies are needed to improve the quality of care given to patients that extend beyond the hospital discharge, a critical point of transition in care.

Indexed as

Acute Coronary SyndromeAdultAgedBrazilCardiovascular AgentsCohort StudiesDrug Therapy, CombinationEvidence-Based MedicineFemaleHumansMaleMiddle AgedPractice Guidelines as TopicSecondary PreventionCardiovascular Agents

Identifiers

PMID26759968
PMCPMC4687825
OpenAlexW2270152400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.