Evidence map›Paper›PMID 26759794›Full record

ReviewJournal of International Society of Preventive & Community Dentistry

Critical evaluation of incidence and prevalence of white spot lesions during fixed orthodontic appliance treatment: A meta-analysis.

Dhinahar Sundararaj, Sudhakar Venkatachalapathy, Akshay Tandon, Aaron Pereira

5 registry-linked trialsOpen access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of International Society of Preventive & Community Dentistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 117 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
117citing papers in PubMed, 10 pooled it
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04528134 nacompletednot on this map

The Effect of Light-cured Fluoride Varnish to Remineralize Post-orthodontic White Spot Lesions and Change the Oral Microbiome: a Double-blind, Split-mouth Randomized Clinical Trial

TypeinterventionalSponsorUniversity of California, Los AngelesRan2022 to 2025Enrolled38ConditionsDental Caries, Dental Plaque, Dental White SpotArmsExtended Contact RMGI (Resin-modified Glass Ionomer) Varnish, 5% Sodium Fluoride Varnish
NCT05764187 nacompletednot on this map

Incidence of White Spot Lesions Around Ceramic Brackets Compared With Metal Brackets Evaluated With Quantitative Light-induced Fluorescence: A Randomized Clinical Trial

TypeinterventionalSponsorJordan University of Science and TechnologyRan2021 to 2022Enrolled51ConditionsWhite Spot Lesion of ToothArmsOrthodontic fixed appliance therapy
NCT05979805 narecruitingnot on this map

Effectiveness of Motivational Interviewing and Conventional Oral Health Education (OHEc) Versus OHEc in the Prevention and Control of Dental Caries and Gingivitis in Subjects With Fixed Orthodontic Appliances. A Randomized Controlled Trial

TypeinterventionalSponsorUniversidad Nacional de ColombiaRan2024 to 2026Enrolled94ConditionsDental Caries, Tooth Demineralization, GingivitisArmsConventional Educational interventions, Motivational intervention
NCT06616207 phase2active not recruitingnot on this map

Efficacy and Safety of Topical 10% Povidone-Iodine in Preventing White Spots During Orthodontic Treatment

TypeinterventionalSponsorUniversity of WashingtonRan2024 to 2027Enrolled80ConditionsWhite Spot Lesions, Gingival Inflammation and BleedingArmsPlacebo, Povidone-iodine solution
NCT06752291 naactive not recruitingnot on this map

EFFECTIVENESS of WATER FLOSS in PLAQUE REMOVAL and PREVENTION of WHITE SPOT LESIONS in ORTHODONTIC PATIENTS: a RANDOMISED CONTROLLED CLINICAL TRIAL

TypeinterventionalSponsorUniversity of MalayaRan2024 to 2026Enrolled32ConditionsWhite Spot Lesion of Tooth, Gingival Inflammation, Gingival Bleeding, Dental PlaqueArmswater flosser
3 · Its place in the literature

Who cites it

117 citing papers in PubMed, 10 syntheses or guidelines pooled it, 269 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. White Spots: Prevention in Orthodontics-Systematic Review of the Literature.International journal of environmental research and public health · 2023
    Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Trial
  12. Trial
  13. Trial
  14. Trial
  15. Trial
  16. Effectiveness of WaterpikJournal of orthodontics · 2023
    Trial
  17. Evaluation of Nano TiOBiological trace element research · 2023
    Trial
  18. Use of bioluminescence measurements for detection of artificial demineralization adjacent to orthodontic brackets.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2023
    Trial
  19. Trial
  20. Effect of the caries-protective self-assembling peptide P11-4 on shear bond strength of metal brackets.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2021
    Trial

57 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Dhinahar SundararajDepartment of Orthodontics and Dentofacial Orthopedics, SRM Kattankulathur Dental College and Hospital, SRM University, Kancheepuram, Tamil Nadu, India.
Sudhakar VenkatachalapathyDepartment of Orthodontics and Dentofacial Orthopedics, SRM Kattankulathur Dental College and Hospital, SRM University, Kancheepuram, Tamil Nadu, India.
Akshay TandonDepartment of Orthodontics and Dentofacial Orthopedics, SRM Kattankulathur Dental College and Hospital, SRM University, Kancheepuram, Tamil Nadu, India.
Aaron PereiraDepartment of Orthodontics and Dentofacial Orthopedics, SRM Kattankulathur Dental College and Hospital, SRM University, Kancheepuram, Tamil Nadu, India.
SRM Dental College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveDevelopment of dental caries, specifically, white spot lesions (WSLs), continues to be a well-recognized and troubling side effect of orthodontic fixed appliance therapy, despite vast improvement in preventive dental techniques and procedures. The aim of this meta-analysis is to evaluate, determine, and summarize the incidence and prevalence rates of WSLs during orthodontic treatment that have been published in the literature. MATERIALS AND

methodsAccording to predetermined criteria, databases were searched for appropriate studies. References of the selected articles and relevant reviews were searched for any missed publications.

resultsIn the 14 studies evaluated for WSLs, the incidence of new carious lesions formed during orthodontic treatment in patients was 45.8% and the prevalence of lesions in patients undergoing orthodontic treatment was 68.4%.

conclusionThe incidence and prevalence rates of WSLs in patients undergoing orthodontic treatment are quite high and significant. This widespread problem of WSL development is an alarming challenge and warrants significant attention from both patients and providers, which should result in greatly increased emphasis on effective caries prevention.

Indexed as

Demineralizationincidenceorthodontic fixed appliancesprevalencewhite spot lesions

Identifiers

PMID26759794
PMCPMC4697225
OpenAlexW2279707762

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.