Evidence map›Paper›PMID 26759641›Full record

ArticleThe western journal of emergency medicine2015

Abdominal CT Does Not Improve Outcome for Children with Suspected Acute Appendicitis.

Danielle I Miano, Renee M Silvis, Jill M Popp, Marvin C Culbertson, Brendan Campbell, Sharon R Smith

Open access · goldAbstract read
In one paragraph

Article in The western journal of emergency medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Pediatric appendicitis in the time of the COVID-19 pandemic: A retrospective chart review.Journal of the American College of Emergency Physicians open · 2022
    Article
  4. Article
  5. Overuse of CT and MRI in paediatric emergency departments.The British journal of radiology · 2018
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Danielle I MianoConnecticut Children's Medical Center, Department of Research, Hartford, Connecticut; University of Connecticut School of Medicine, Farmington, Connecticut.
Renee M SilvisConnecticut Children's Medical Center, Department of Research, Hartford, Connecticut.
Jill M PoppConnecticut Children's Medical Center, Department of Research, Hartford, Connecticut.
Marvin C CulbertsonConnecticut Children's Medical Center, Department of Emergency Medicine, Hartford, Connecticut.
Brendan CampbellConnecticut Children's Medical Center, Department of Surgery, Hartford, Connecticut.
Sharon R SmithConnecticut Children's Medical Center, Department of Emergency Medicine, Hartford, Connecticut.
Hartford Financial Services (United States)Connecticut Children's Medical Center · USUniversity of Connecticut · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAcute appendicitis in children is a clinical diagnosis, which often requires preoperative confirmation with either ultrasound (US) or computed tomography (CT) studies. CTs expose children to radiation, which may increase the lifetime risk of developing malignancy. US in the pediatric population with appropriate clinical follow up and serial exam may be an effective diagnostic modality for many children without incurring the risk of radiation. The objective of the study was to compare the rate of appendiceal rupture and negative appendectomies between children with and without abdominal CTs; and to evaluate the same outcomes for children with and without USs to determine if there were any associations between imaging modalities and outcomes.

methodsWe conducted a retrospective chart review including emergency department (ED) and inpatient records from 1/1/2009-2/31/2010 and included patients with suspected acute appendicitis.

results1,493 children, aged less than one year to 20 years, were identified in the ED with suspected appendicitis. These patients presented with abdominal pain who had either a surgical consult or an abdominal imaging study to evaluate for appendicitis, or were transferred from an outside hospital or primary care physician office with the stated suspicion of acute appendicitis. Of these patients, 739 were sent home following evaluation in the ED and did not return within the subsequent two weeks and were therefore presumed not to have appendicitis. A total of 754 were admitted and form the study population, of which 20% received a CT, 53% US, and 8% received both. Of these 57%, 95% CI [53.5,60.5] had pathology-proven appendicitis. Appendicitis rates were similar for children with a CT (57%, 95% CI [49.6,64.4]) compared to those without (57%, 95% CI [52.9,61.0]). Children with perforation were similar between those with a CT (18%, 95% CI [12.3,23.7]) and those without (13%, 95% CI [10.3,15.7]). The proportion of children with a negative appendectomy was similar in both groups: CT (7%, 95% CI [2.1,11.9]), US (8%, 95% CI [4.7,11.3]) and neither (12%, 95% CI [5.9,18.1]).

conclusionIn this uncontrolled study, the accuracy of preoperative diagnosis of appendicitis and the incidence of pathology-proven perforation appendix were similar for children with suspected acute appendicitis whether they had CT, US or neither imaging, in conjunction with surgical consult. The imaging modality of CT was not associated with better outcomes for children presenting to the ED with suspected appendicitis.

Indexed as

Acute DiseaseAdolescentAge DistributionAppendectomyAppendicitisChildChild, PreschoolEarly DiagnosisEmergency Service, HospitalEmergency TreatmentFemaleHospitalizationHumansInfantInfant, NewbornMale

Identifiers

PMID26759641
PMCPMC4703157
OpenAlexW2194931471

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.