ReviewJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences2015
Diagnosis and treatment of patients with nonacid gastroesophageal reflux-induced chronic cough.
Review in Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Gastroesophageal Reflux Burden Before and After Exercise Challenge in Children with Poorly Controlled Asthma: A 48-Hour MII-pH Study.Advances in respiratory medicine · 2026Article
- Article
- Clarifying Terminology in Chronic Cough: The Evolving Role of Cough Hypersensitivity Syndrome.The clinical respiratory journal · 2026Review
- Somatic Symptom Disorder Is Associated with Cough Hypersensitivity and Poor Response to Anti-Reflux Therapy in Patients with Gastroesophageal Reflux-Induced Chronic Cough.Journal of clinical medicine · 2026Article
- Predictive factors for neuromodulator response in patients with nonacid gastroesophageal reflux-induced chronic cough: a retrospective data analysis.Therapeutic advances in chronic disease · 2025Article
- Article
- Diagnostic value of the pepsin concentration in saliva and induced sputum for gastroesophageal reflux-induced chronic cough: a prospective clinical study.ERJ open research · 2024Article
- Narrative review of relationship between chronic cough and laryngopharyngeal reflux.Frontiers in medicine · 2024Review
- Mean Nocturnal Baseline Impedance (MNBI) Provides Evidence for Standardized Management Algorithms of Nonacid Gastroesophageal Reflux-Induced Chronic Cough.International journal of clinical practice · 2023Article
- Diagnostic value of reflux episodes in gastroesophageal reflux-induced chronic cough: a novel predictive indicator.Therapeutic advances in chronic disease · 2022Article
- GERD-related chronic cough: Possible mechanism, diagnosis and treatment.Frontiers in physiology · 2022Review
- Changes in Cough Reflex Sensitivity in Children After Removal of Hypertrophied Adenoid Tissue.Journal of asthma and allergy · 2022Article
- Chronic cough caused by choledochoduodenal fistula: a case report.BMC pulmonary medicine · 2021Article
- Gastroesophageal reflux disease and chronic cough: A possible mechanism elucidated by ambulatory pH-impedance-pressure monitoring.Neurogastroenterology and motility · 2019Article
- Reflux characteristics in patients with gastroesophageal reflux-related chronic cough complicated by laryngopharyngeal reflux.Annals of translational medicine · 2019Article
- Comparison of Characteristics According to Reflux Type in Patients With Laryngopharyngeal Reflux.Clinical and experimental otorhinolaryngology · 2018Article
- The relationship between fruit and vegetable intake with gastroesophageal reflux disease in Iranian adults.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2017Article
- Cough modulation by upper airway stimuli in cat - potential clinical application?Open journal of molecular and integrative physiology · 2016Article
- Post-reflux swallow-induced peristaltic wave index: a new parameter for the identification of non-acid gastroesophageal reflux-related chronic cough.Therapeutic advances in respiratory diseaseArticle
- Gastroesophageal reflux-induced cough: the positive feedback loop of microaspiration and neurogenic inflammation.Therapeutic advances in respiratory diseaseReview
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gastroesophageal reflux (GER) is one of the most common causes of chronic cough, and chronic cough due to GER represents a subtype of GER-related diseases. Gastroesophageal reflux-induced chronic cough (GERC) can be divided into two subgroups based on the pH of the GER. Nonacid GERC is less common than acid GERC, and its diagnosis and treatment strategy have not been standardized. However, nonacid GERC usually presents with its unique set of characteristics and features upon diagnosis and treatment in the clinic. Although the underlying molecular mechanism of nonacid GERC is not fully understood, it is considered to be associated with reflux theory, reflex theory and airway hypersensitivity. Multi-channel intraluminal impedance combined with pH monitoring is a promising new technique that can detect both acid and nonacid reflux, and our findings as well as those of others have shown its usefulness in diagnosing nonacid GERC. Development of new diagnostic techniques has led to an increased rate of nonacid GERC diagnosis. We summarize our experience in the diagnosis and treatment of nonacid GERC and provide a guide for future therapeutic approaches.
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