ArticleNigerian medical journal : journal of the Nigeria Medical Association
Comparative study of intralesional steroid injection and cryotherapy in alopecia areata.
Article in Nigerian medical journal : journal of the Nigeria Medical Association. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed, 37 citations in OpenAlex.
- Treatment Outcomes of Triamcinolone Acetonide Compared with Cryotherapy in Alopecia Areata: Evidence from a Systematic Review and Meta-Analysis.Dermatology practical & conceptual · 2026Article
- Intralesional Corticosteroid Versus Cryotherapy for Alopecia Areata: A Systematic Review and Meta-analysis.Acta dermato-venereologica · 2025Article
- Guidelines for the Management of Patients with Alopecia Areata in Korea: Part I Topical and Device-based Treatment.Annals of dermatology · 2023Article
- A Prospective Study to Compare the Efficacy of Cryotherapy Versus Intralesional Steroid in Alopecia Areata.Journal of cutaneous and aesthetic surgeryArticle
- Liquid Nitrogen Cryotherapy in Recalcitrant Alopecia Areata: A Study of 11 Patients.International journal of trichologyArticle
- IADVL SIG Pediatric Dermatology (Academy) Recommendations on Childhood Alopecia Areata.Indian dermatology online journalReview
- Comparative Evaluation of Therapeutic Efficacy of Intralesional Injection of Triamcinolone Acetonide versus Intralesional Autologous Platelet-rich Plasma Injection in Alopecia Areata.Journal of cutaneous and aesthetic surgeryArticle
- Superficial Cryotherapy versus Intralesional Corticosteroids Injection in Alopecia Areata: A Trichoscopic Comparative Study.International journal of trichologyArticle
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7 authors at 2 institutions in 1 country.
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Abstract
BACKGROUND AND
objectivesAlopecia areata (AA) is a common, non-scarring type of hair loss, affecting approximately 2.1% of the population, many modality of treatment recommended like steroid injection, topical Immunotherapy and several systemic therapies. The aim of this study was to compare intralesional steroid injection and cryotherapyoutcomes in AA. MATERIALS AND
methodsIn an analytical-descriptive study, 120 AA patients treated with intralesionalsteroid injection and 120 AA patients treated with cryotherapy were randomly selected. These two groups matched for location, duration and size of lesion and also matched for age and gender. From March 2011 to September 2013, the effect and complications of the therapies after 3, 6, 9 and 12 weeks were assessed and results were compared between the two groups.
resultsMean age of patients in steroid injection group was 30.2 ± 6.8 and in cryotherapy group was 31.8 ± 7.1. Sexual distribution in both groups was 56.7% and 43.3 % for male and female, respectively. Location of disease in 80% was in scalp and 20% was in face in both groups. The time of beginning response in steroid group was 4.13 ± 2.13 weeks and in cryotherapy group was 6.14 ± 0.29 weeks, difference between two groups was significant (P = 0.001). In term of clinical response at the end of study, in steroid group,20 patients (16.7%) no response, 32 patients (26.7%), moderate response and68 patients (56.7%) had a complete response, and also in cryotherapy group was, 52 patients (43.3%) no response, 40 patients (33.3%) moderate response and 28 patients (23.3%) had a complete response. There was significant different in complete response rate and steroid injection was more effective than cryotherapy(P < 0.05).
conclusionAs the cryotherapy isa considerable treatment of AA, alsothis study proposes intralesional injection of corticosteroid, as a replacement of AA therapy; particularly the short-term complications are not significantly different.
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