Evidence map›Paper›PMID 26759327›Full record

ReviewInternational urology and nephrology2016

New molecular insights in diabetic nephropathy.

Ionel Alexandru Checheriţă, Gina Manda, Mihai Eugen Hinescu, Ileana Peride, Andrei Niculae, Ştefana Bîlha, Angelica Grămăticu, Luminiţa Voroneanu, Adrian Covic

Abstract readReview
PubMed Publisher
In one paragraph

Review in International urology and nephrology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Ionel Alexandru ChecheriţăClinical Department No 3, "Carol Davila" University of Medicine and Pharmacy, 37th Dionisie Lupu Street, Sector 1, 020022, Bucharest, Romania.
Gina Manda"Victor Babes" National Institute of Pathology, Bucharest, Romania.
Mihai Eugen Hinescu"Victor Babes" National Institute of Pathology, Bucharest, Romania.
Ileana PerideClinical Department No 3, "Carol Davila" University of Medicine and Pharmacy, 37th Dionisie Lupu Street, Sector 1, 020022, Bucharest, Romania. ileana_peride@yahoo.com.
Andrei NiculaeClinical Department No 3, "Carol Davila" University of Medicine and Pharmacy, 37th Dionisie Lupu Street, Sector 1, 020022, Bucharest, Romania.
Ştefana BîlhaDepartment of Internal Medicine I, "Grigore T. Popa" University of Medicine and Pharmacy, Iasi, Romania.
Angelica GrămăticuDepartment of Internal Medicine I, "Grigore T. Popa" University of Medicine and Pharmacy, Iasi, Romania.
Luminiţa VoroneanuDepartment of Internal Medicine I, "Grigore T. Popa" University of Medicine and Pharmacy, Iasi, Romania.
Adrian CovicDepartment of Internal Medicine I, "Grigore T. Popa" University of Medicine and Pharmacy, Iasi, Romania.
Spitalul Clinic Dr. C. I. Parhon · ROClinical Emergency Hospital Bucharest · ROInstitutul National Victor Babes · ROCarol Davila University of Medicine and Pharmacy · ROGrigore T. Popa University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes mellitus represents one of the major causes of functional kidney impairment. The review highlights the most significant steps made over the last decades in understanding the molecular basis of diabetic nephropathy (DN), which may provide reliable biomarkers for early diagnosis and prognosis, along with new molecular targets for personalized medicine. There is an increased interest in developing new therapeutic strategies to slow DN progression for improving patients' quality of life and reducing all-cause morbidity and disease-associated mortality. It is highly important to have a science-based medical attitude when facing diabetic patients with associated comorbidities and risk of rapid evolution toward end-stage renal disease. The data discussed herein were mainly from MEDLINE and PubMed articles published in English from 1990 to 2015 and from up-to-date. The search term was "diabetic nephropathy and oxidative stress".

Indexed as

Oxidative StressBiomarkersDiabetic NephropathiesHumansPrognosisBiomarkersDiabetic nephropathyInflammationOxidative stressPrognosisTherapy

Identifiers

PMID26759327
OpenAlexW2237439154

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.