Evidence map›Paper›PMID 26759100›Full record

ArticleZhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi2015

[Impacts of ABO incompatibility on early outcome after single unit unrelated cord blood transplantation: a retrospective single center experience].

Jiawei Yan, Guangyu Sun, Lei Zhang, Wen Yao, Xiaoyu Zhu, Baolin Tang, Changcheng Zheng, Huilan Liu, Zimin Sun

Open access · greenAbstract read
In one paragraph

Article in Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jiawei YanDepartment of Hematology, Affiliated Provincial Hospital, Anhui Medical University, Hefei 230001, China.
Guangyu SunDepartment of Hematology, Affiliated Provincial Hospital, Anhui Medical University, Hefei 230001, China.
Lei ZhangDepartment of Hematology, Affiliated Provincial Hospital, Anhui Medical University, Hefei 230001, China.
Wen YaoDepartment of Hematology, Affiliated Provincial Hospital, Anhui Medical University, Hefei 230001, China.
Xiaoyu ZhuDepartment of Hematology, Affiliated Provincial Hospital, Anhui Medical University, Hefei 230001, China.
Baolin TangDepartment of Hematology, Affiliated Provincial Hospital, Anhui Medical University, Hefei 230001, China.
Changcheng ZhengDepartment of Hematology, Affiliated Provincial Hospital, Anhui Medical University, Hefei 230001, China.
Huilan LiuDepartment of Hematology, Affiliated Provincial Hospital, Anhui Medical University, Hefei 230001, China.
Zimin SunDepartment of Hematology, Affiliated Provincial Hospital, Anhui Medical University, Hefei 230001, China.
Anhui Provincial Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo retrospectively study the impacts of ABO incompatibility on early outcome after single unit unrelated cord blood transplantation(UCBT), such as cumulative incidence of engraftment, incidence of acute graft- versus- host disease (aGVHD) and 180- day transplant- related mortality(TRM).

methods208 patients underwent single unit UCBT from April 2008 to October 2014 were analyzed, included 99 ABO- identical, 60 minor, 38 major and 11 bidirectional ABO- incompatible recipients. All the patients received intensified myeloablative conditioning, and a combination of cyclosporine A and mycophenolate mofetil was given for GVHD prophylaxis.

resultsCumulative incidences of neutrophil engraftment, platelet recovery, erythroid lineage reconstitution, Ⅱ-Ⅳ aGVHD, Ⅲ-Ⅳ aGVHD and 180- day TRM showed no significant difference among the patients receiving ABOidentical, minor, major, and bidirectional UCBT(all P>0.05, respectively). What's more, none of the patients developed pure red- cell aplasia(PRCA)after UCBT. Group A donor and a group O recipient patients didn't appeared to influence the clinical results when compared with others(all P>0.05, respectively).

conclusionPatients receive ABO- incompatible UCBT may not develop PRCA. The presence of ABO- incompatibility did not influence the hematopoietic reconstitution, the incidence of aGVHD and 180-day TRM in this cohort. There is not support for the need to regard ABO-compatibility as an UCB-graft selection criterion.

Indexed as

ABO Blood-Group SystemBlood Group IncompatibilityCord Blood Stem Cell TransplantationCyclosporineGraft vs Host DiseaseHumansMycophenolic AcidRed-Cell Aplasia, PureRetrospective StudiesTissue DonorsTransplantation, HomologousABO Blood-Group SystemCyclosporineMycophenolic Acid

Identifiers

PMID26759100
PMCPMC7342320
OpenAlexW2236596410

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.