ReviewIntensive care medicine2016
Positive and negative effects of mechanical ventilation on sleep in the ICU: a review with clinical recommendations.
Review in Intensive care medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 45 citations in OpenAlex.
- Risk factors and prediction model for sleep disorders in respiratory critically ill patients after intensive care unit transfer.American journal of translational research · 2026Article
- Optimizing Sleep Hygiene in the Hospital Environment.Sleep medicine clinics · 2025Review
- Electroencephalography-based evaluation of the impact of night-time nursing care on sleep during intensive care unit administration after cardiac surgery.Scientific reports · 2025Article
- Sleep Quality and Disruptive Factors in Intensive Care Units: A Comparison Between Mechanically Ventilated and Spontaneously Breathing Patients.Nursing in critical care · 2025Observational
- Translation and Validation of the Richards-Campbell Sleep Questionnaire for Intensive Care Unit Patients in Morocco: Reliability and Validity Assessment.Clocks & sleep · 2025Article
- Effect of sleep quality on weaning from mechanical ventilation: A scoping review.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2025Review
- Factors Associated with and Prognosis Impact of Perceived Sleep Quality and Estimated Quantity in Patients Receiving Non-Invasive Ventilation for Acute Respiratory Failure.Journal of clinical medicine · 2022Article
- Early Intensive Physical Rehabilitation Combined with a Protocolized Decannulation Process in Tracheostomized Survivors from Severe COVID-19 Pneumonia with Chronic Critical Illness.Journal of clinical medicine · 2022Article
- Sleep Architecture in Mechanically Ventilated Pediatric ICU Patients Receiving Goal-Directed, Dexmedetomidine- and Opioid-based Sedation.Journal of pediatric intensive care · 2022Article
- A best evidence synthesis in practicing early active movements in ICU patients with mechanical ventilation.American journal of translational research · 2021Article
- Effects of deep sedation on sleep in critically ill medical patients on mechanical ventilation.Journal of sleep research · 2020Article
- Validity of an under-mattress sensor for objective sleep measurement in critically ill patients: a prospective observational study.Journal of intensive care · 2020Article
- The effects of mechanical ventilation on the quality of sleep of hospitalised patients in the Intensive Care Unit.Romanian journal of anaesthesia and intensive care · 2018Review
- Promoting Sleep in the Intensive Care Unit.SAGE open nursingArticle
- Patient-ventilator asynchrony.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e TisilogiaReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeSleep is an essential physiologic process that helps to restore normal body homeostasis. Sleep disturbances have been shown to be associated with poor clinical outcomes, such as a greater risk of cardiovascular disease and increasing mortality. Critically ill patients, particularly those receiving mechanical ventilation, may be more susceptible to sleep disruption. METHODS AND
resultsMechanical ventilation is an important factor influencing sleep in critically ill patients as it may have positive or negative effects, depending on patient population, mode, and specific settings. Other causes of sleep disruption include the acute illness itself, the daily routine care, and the effects of medications. Improving sleep in patients admitted to an intensive care unit has the potential to improve both short- and long-term clinical outcomes. In this article we review the specific aspects of sleep in critically ill mechanically ventilated patients, including abnormal sleep patterns and loss of circadian rhythm, as well as the effects of mechanical ventilation and intravenous sedatives on sleep quality and quantity.
conclusionsWe provide recommendations for clinicians regarding optimal ventilatory settings and discuss fields for future research.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.