ArticleJournal of exposure science & environmental epidemiology2017
Stochastic modeling of near-field exposure to parabens in personal care products.
Article in Journal of exposure science & environmental epidemiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed.
- USEtox modeling of children's exposures to Bisphenol A (BPA) and alternatives in toys.Journal of exposure science & environmental epidemiology · 2026Article
- Exposure Prioritization (Toxics · 2022Article
- Exposure modelling in Europe: how to pave the road for the future as part of the European Exposure Science Strategy 2020-2030.Journal of exposure science & environmental epidemiology · 2022Review
- A modular mechanistic framework for estimating exposure to SVOCs: Next steps for modeling emission and partitioning of plasticizers and PFAS.Journal of exposure science & environmental epidemiology · 2022Review
- Article
- Exposure and Toxicity Characterization of Chemical Emissions and Chemicals in Products: Global Recommendations and Implementation in USEtox.The international journal of life cycle assessment · 2021Article
- Personal care product use among diverse women in California: Taking Stock Study.Journal of exposure science & environmental epidemiology · 2021Article
- High Throughput Risk and Impact Screening of Chemicals in Consumer Products.Risk analysis : an official publication of the Society for Risk Analysis · 2021Article
- Building a European exposure science strategy.Journal of exposure science & environmental epidemiology · 2020Review
- Qualitative approach to comparative exposure in alternatives assessment.Integrated environmental assessment and management · 2019Article
- Integrating exposure to chemicals in building materials during use stage.The international journal of life cycle assessment · 2019Article
- Advancements in Life Cycle Human Exposure and Toxicity Characterization.Environmental health perspectives · 2018Article
- High-throughput exposure modeling to support prioritization of chemicals in personal care products.Chemosphere · 2016Article
- Conceptual Framework To Extend Life Cycle Assessment Using Near-Field Human Exposure Modeling and High-Throughput Tools for Chemicals.Environmental science & technology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Exposure assessment is a key step in determining risks to chemicals in consumer goods, including personal care products (PCPs). Exposure models can be used to estimate exposures to chemicals in the absence of biomonitoring data and as tools in chemical risk prioritization and screening. We apply a PCP exposure model based on the product intake fraction (PiF), which is defined as the fraction of chemical in a product that is taken in by the exposed population, to estimate chemical intake based on physicochemical properties and PCP usage characteristics. The PiF can be used to estimate route and pathway-specific exposures during both the use and disposal stages of a product. As a case study, we stochastically quantified population level exposures to parabens in PCPs, and compared estimates with biomarker values. We estimated exposure based on the usage of PCPs in the female US population, taking into account population variability, product usage characteristics, paraben occurrence in PCPs and the PiF. Intakes were converted to urine levels and compared with National Health and Nutrition Examination Survey (NHANES) biomonitoring data. Results suggest that for parabens, chemical exposure during product use is substantially larger than environmentally mediated exposure after product disposal. Modeled urine concentrations reflect well the NHANES variation of three orders of magnitude across parabens for the 50
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.