SynthesisScientific reports2016
Parity and All-cause Mortality in Women and Men: A Dose-Response Meta-Analysis of Cohort Studies.
Synthesis in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 88 citations in OpenAlex.
- Female infertility and long-term cardiovascular risk: a systematic review and meta-analysis.Endocrine · 2026Pooled it
- Are pregnancy and parity associated with telomere length? A systematic review.BMC pregnancy and childbirth · 2023Pooled it
- Parity and heart failure risk in diabetic women with coronary artery disease: a multicentre cohort study.ESC heart failure · 2026Article
- The relationship between parity and late-life frailty: companion dogs as a preclinical model for evaluating factors that aggravate or mitigate the frailty cost of reproduction.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026Article
- Single-nucleus profiling reveals age-associated remodeling opposed by parity in the postmenopausal human ovary.bioRxiv : the preprint server for biology · 2026Article
- Pregnancy lab test dynamics resemble rejuvenation of some organs and aging of others.Nature communications · 2026Article
- Birthplace, perinatal loss, and the parity-post-reproductive mortality relationship: Evidence from the Jim Crow-era American South.Social science & medicine (1982) · 2026Article
- Association between parenthood and survival among 30,386 patients hospitalized with COVID-19.PloS one · 2026Article
- Association of grand multiparity with adverse birth outcomes and sociodemographic characteristics: an analysis of nationwide birth data in Japan.Reproductive health · 2025Article
- Association of parity with the timing and type of menopause: a longitudinal cohort study.American journal of epidemiology · 2025Article
- Caregiving is associated with lower brain age in humans.Social cognitive and affective neuroscience · 2025Article
- Parenthood and all-cause mortality in older adults with schizophrenia: a multicenter 5-year prospective study.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2025Article
- Immune transcriptomic profile in adult female pigs: dominance status has more influence than environmental enrichment.BMC genomics · 2024Article
- Comparison of Cranial Cruciate Ligament Rupture Incidence among Parous and Nulliparous Rottweiler Bitches: Evidence from a Lifetime Cohort Study Supporting a Paradigm of Pregnancy-Associated Protection against Subsequent Non-Reproductive Disease Outcomes.Animals : an open access journal from MDPI · 2024Article
- Assessing the health impacts of parenthood on people with cystic fibrosis: the HOPeCF prospective cohort protocol.BMJ open respiratory research · 2024Observational
- Pregnancy is linked to faster epigenetic aging in young women.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Parity and post-reproductive mortality among U.S. Black and White women: Evidence from the health and retirement study.PloS one · 2024Article
- Correlates of estimated lifetime cruciate ligament survival inform potential rupture risk reduction strategies: findings from the Exceptional Aging in Rottweilers Study.Scientific reports · 2023Article
- Association between the number of pregnancies and cardiac target organ damages: a cross-sectional analysis of data from the Korean women's chest pain registry (KoROSE).BMC women's health · 2023Article
- Mothers of small-bodied children and fathers of vigorous sons live longer.Frontiers in public health · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To quantitatively assess the association between parity and all-cause mortality, we conducted a meta-analysis of cohort studies. Relevant reports were identified from PubMed and Embase databases. Cohort studies with relative risks (RRs) and 95% confidence intervals (CIs) of all-cause mortality in three or more categories of parity were eligible. Eighteen articles with 2,813,418 participants were included. Results showed that participants with no live birth had higher risk of all-cause mortality (RR= 1.19, 95% CI = 1.03-1.38; I(2) = 96.7%, P < 0.001) compared with participants with one or more live births. Nonlinear dose-response association was found between parity and all-cause mortality (P for non-linearity < 0.0001). Our findings suggest that moderate-level parity is inversely associated with all-cause mortality.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.