Evidence map›Paper›PMID 26757924›Full record

ArticleObesity surgery2016

Glucose Profiles in Pregnant Women After a Gastric Bypass : Findings from Continuous Glucose Monitoring.

Camille Bonis, Françoise Lorenzini, Monelle Bertrand, Olivier Parant, Pierre Gourdy, Charlotte Vaurs, Laurent Cazals, Patrick Ritz, Hélène Hanaire

Abstract read
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In one paragraph

Article in Obesity surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Camille BonisDepartment of Diabetology, Metabolic Diseases, and Nutrition, CHU Toulouse, Toulouse, France.
Françoise LorenziniDepartment of Diabetology, Metabolic Diseases, and Nutrition, CHU Toulouse, Toulouse, France.
Monelle BertrandNutrition Unit, Cardiovascular and Metabolism Division, Larrey Hospital, CHU of Toulouse, Toulouse, France.
Olivier ParantDepartment of Obstetrics and Gynecology, Paule de Viguier Hospital, CHU of Toulouse, Toulouse, France.
Pierre GourdyDepartment of Diabetology, Metabolic Diseases, and Nutrition, CHU Toulouse, Toulouse, France.
Charlotte VaursDepartment of Diabetology, Metabolic Diseases, and Nutrition, CHU Toulouse, Toulouse, France.
Laurent CazalsDepartment of Diabetology, Metabolic Diseases, and Nutrition, CHU Toulouse, Toulouse, France.
Patrick RitzNutrition Unit, Cardiovascular and Metabolism Division, Larrey Hospital, CHU of Toulouse, Toulouse, France.
Hélène HanaireDepartment of Diabetology, Metabolic Diseases, and Nutrition, CHU Toulouse, Toulouse, France. hanaire.h@chu-toulouse.fr.
Unité de recherche sur les maladies cardiovasculaires et métaboliques · FRHôpital Larrey · FRHôpital Paule de Viguier · FRUniversité de Toulouse · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe diagnosis of gestational diabetes mellitus (GDM) usually requires an oral glucose tolerance test, but this procedure seems inappropriate after gastric bypass surgery (Roux-en-Y gastric bypass (RYGB)) due to specific altered glycemic responses. We aimed here at describing continuous glucose monitoring (CGM) profile of pregnant women after RYGB.

methodsCGM was performed in 35 consecutive pregnant women after RYGB at 26.2 ± 5 weeks of gestation.

resultsAfter RYGB, pregnant women display high postprandial interstitial glucose (IG) peaks and low IG before and 2 h after meals. The postprandial IG peak is reached early, within 54 ± 9 min. The maximum IG values reach 205 mg/dl, and the percentage of time above 140 mg/dl (6.6 ± 7 %) is similar to what is described in GDM women.

conclusionsThis study is the first to describe CGM profile in pregnant women after RYGB. CGM features are similar to those of non-pregnant post-RYGB patients, characterized by wide and rapid changes in postprandial IG, and high exposure to hyperglycemia. The exposure to hyperglycemia is similar to what is reported in GDM although the time to postprandial peak is shorter. CGM could be an additional useful approach to screen for glucose intolerance during pregnancy after RYGB.

Indexed as

Gastric BypassObesity, MorbidPregnancy ComplicationsAdultBlood GlucoseCohort StudiesFemaleHumansMonitoring, PhysiologicPostprandial PeriodPregnancyBlood GlucoseBlood glucose self monitoringContinuous glucose monitoringGastric bypassGestational diabetes(MESH) bariatric surgeryPregnancy

Identifiers

PMID26757924
OpenAlexW2247688561

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.