Evidence map›Paper›PMID 26757849›Full record

ReviewExpert review of clinical immunology2016

An Overview of Fractional Exhaled Nitric Oxide and Children with Asthma.

Devika R Rao, Wanda Phipatanakul

Open access · greenAbstract readReview
In one paragraph

Review in Expert review of clinical immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
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  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Devika R Raoa Division of Respiratory Medicine, Department of Pediatrics , University of Texas Southwestern Medical Center , Dallas , TX , USA.
Wanda Phipatanakulb The Channing Division of Network Medicine , Brigham and Women's Hospital , Boston , MA , USA.
Brigham and Women's Hospital · USThe University of Texas Southwestern Medical Center · US

Funding

AsthmaNet: Brigham and Women's Hospital & Children's Hospital BostonU10HL098102 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI ISRAEL, ELLIOT, PHIPATANAKUL, WANDA · 2009 to 2015
$5.5M
AMSA: ALXR/FBR Mediated Signaling in Severe AsthmaU10HL109172 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI ISRAEL, ELLIOT, LEVY, BRUCE D · 2011 to 2016
$4.2M
Midcareer Investigator Award: Urban School Allergen Exposures and Childhood AsthmK24AI106822 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI PHIPATANAKUL, WANDA · 2013 to 2022
$1.9M
NHLBI NIH HHS U10 HL098102NHLBI NIH HHS U10HL098102NHLBI NIH HHS U10 HL109172NHLBI NIH HHS U10HL109172NIAID NIH HHS K24 AI 106822NIAID NIH HHS K24 AI106822
6 · The paper itself

Abstract

Asthma is the most common pediatric chronic disease and is characterized by lung inflammation. Fractional exhaled nitric oxide (FeNO) is thought to reflect the presence of eosinophilic airway inflammation, and is an easy, non-invasive test that has held promise in providing additional objective data. However, not all studies have shown a clinical benefit in the use of FeNO to guide management of asthma in children. This review will describe the results of the most recent studies examining the use of FeNO in the diagnosis and treatment of asthma in infants, preschool-aged children and in school-aged children. It will aid the clinician in providing a clinical context in which FeNO may be most useful in treating pediatric asthma.

Indexed as

AsthmaChildChild, PreschoolDisease ManagementExhalationFemaleHumansInfantMaleNitric OxideNitric OxideFractional exhaled nitric oxideinfant lung functionlung functionpediatric asthmasickle cell disease

Identifiers

PMID26757849
PMCPMC4837084
OpenAlexW2235240275

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.