Evidence map›Paper›PMID 26757714›Full record

ArticleTranslational stroke research2016

Translational Stroke Research on Blood-Brain Barrier Damage: Challenges, Perspectives, and Goals.

Yejie Shi, Rehana K Leak, Richard F Keep, Jun Chen

Registry-linked trialAbstract readEditorial
In one paragraph

Article in Translational stroke research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03741530 (Glibenclamide Advantage in Treating Edema After Intracerebral Hemorrhage), which is not on this map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03741530 nacompletednot on this mapstarted 2018, after this paper: background citation

Glibenclamide Advantage in Treating Edema After Intracerebral Hemorrhage (GATE-ICH): a Multi-center Randomized, Controlled, Assessor-blinded Trial

TypeinterventionalSponsorXijing HospitalRan2018 to 2020Enrolled220ConditionsIntracerebral HemorrhageArmsGlibenclamide Tablets, Standard management for ICH
3 · Its place in the literature

Who cites it

51 citing papers in PubMed.

  1. Trial
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  10. Therapeutic Potential of Saffron (Evidence-based complementary and alternative medicine : eCAM · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yejie ShiCenter of Cerebrovascular Disease Research, University of Pittsburgh School of Medicine, S-507 Biomedical Science Tower 3500 Terrace Street, Pittsburgh, PA, 15213, USA.
Rehana K LeakDivision of Pharmaceutical Sciences, Mylan School of Pharmacy, Duquesne University, Pittsburgh, PA, 15282, USA.
Richard F KeepDepartment of Neurosurgery, University of Michigan, Ann Arbor, MI, 48109, USA.
Jun ChenCenter of Cerebrovascular Disease Research, University of Pittsburgh School of Medicine, S-507 Biomedical Science Tower 3500 Terrace Street, Pittsburgh, PA, 15213, USA. chenj2@upmc.edu.

Funding

Neuroprotection in Models of Cerebral IschemiaR01NS045048 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHEN, JUN · 2003 to 2015
$3.1M
MicroRNAs and post-stroke angiogenesisR01NS091175 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHEN, JUN, YIN, KEJIE · 2015 to 2019
$2.5M
Mechanisms of Neurovascular Injury in Cerebral IschemiaR01NS089534 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHEN, JUN · 2014 to 2018
$1.7M
Heat shock proteins and neuroprotection in cerebral ischemiaI01BX002495 · VA · VETERANS HEALTH ADMINISTRATION · PI CHEN, JUN · 2015 to 2020
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BLRD VA I01 BX002495Intramural VA VA999999NINDS NIH HHS NS045048NINDS NIH HHS NS089534NINDS NIH HHS R01 NS045048NINDS NIH HHS R01 NS089534NINDS NIH HHS R01 NS091175
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Translational Research, BiomedicalAnimalsBlood-Brain BarrierHumansStroke

Identifiers

PMID26757714
PMCPMC4808584

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.