ReviewJournal of pathology and translational medicine2016
Sentinel Lymph Node in Breast Cancer: Review Article from a Pathologist's Point of View.
Review in Journal of pathology and translational medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 50 citations in OpenAlex.
- Axillary lymph node dissection offers no survival benefit in breast cancer patients with sentinel lymph node micrometastases after neoadjuvant therapy.Clinical and experimental medicine · 2025Article
- Article
- Out-of-distribution generalization for segmentation of lymph node metastasis in breast cancer.Scientific reports · 2025Article
- Prognosis of isolated tumor cells and use of molecular classification in early stage endometrioid endometrial cancer.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2024Article
- Clonal dominance defines metastatic dissemination in pancreatic cancer.Science advances · 2024Article
- Association between postoperative pathological results and non-sentinel nodal metastasis in breast cancer patients with sentinel lymph node-positive breast cancer.World journal of surgical oncology · 2024Article
- The Role of Nodes and Nodal Assessment in Diagnosis, Treatment and Prediction in ER+, Node-Positive Breast Cancer.Journal of personalized medicine · 2023Review
- Artificial Intelligence in Breast Cancer Diagnosis and Personalized Medicine.Journal of breast cancer · 2023Review
- Predictive factors for dissection-free sentinel node micrometastases in early oral squamous cell carcinoma.Scientific reports · 2023Article
- Generalization of Deep Learning in Digital Pathology: Experience in Breast Cancer Metastasis Detection.Cancers · 2022Article
- Comparative Analysis of Postoperative Complications of Sentinel Node Identification Using the SentiMagCurrent oncology (Toronto, Ont.) · 2022Article
- Fast Segmentation of Metastatic Foci in H&E Whole-Slide Images for Breast Cancer Diagnosis.Diagnostics (Basel, Switzerland) · 2022Article
- Independent assessment of a deep learning system for lymph node metastasis detection on the Augmented Reality Microscope.Journal of pathology informatics · 2022Article
- Ultrasonographic Algorithm for the Assessment of Sentinel Lymph Nodes That Drain the Mammary Carcinomas in Female Dogs.Animals : an open access journal from MDPI · 2020Article
- Attempting to define sentinel node micrometastasis in oral squamous cell carcinoma.Fukushima journal of medical science · 2020Article
- Independent risk factors for axillary lymph node metastasis in breast cancer patients with one or two positive sentinel lymph nodes.BMC women's health · 2020Article
- Performance of Molecular Lymphosonography for Detection and Quantification of Metastatic Involvement in Sentinel Lymph Nodes.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2019Article
- Impact of Deep Learning Assistance on the Histopathologic Review of Lymph Nodes for Metastatic Breast Cancer.The American journal of surgical pathology · 2018Article
- One-step nucleic acid amplification (OSNA): where do we go with it?International journal of clinical oncology · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Breast cancer staging, in particular N-stage changed most significantly due to the advanced technique of sentinel lymph node biopsy two decades ago. Pathologists have more thoroughly examined and scrutinized sentinel lymph node and found increased number of small volume metastases. While pathologists use the strict criteria from the Tumor Lymph Node Metastasis (TNM) Classification, studies have shown poor reproducibility in the application of American Joint Committee on Cancer and International Union Against Cancer/TNM guidelines for sentinel lymph node classification in breast cancer. In this review article, a brief history of TNM with a focus on N-stage is described, followed by innate problems with the guidelines, and why pathologists may have difficulties in assessing lymph node metastases uniformly. Finally, clinical significance of isolated tumor cells, micrometastasis, and macrometastasis is described by reviewing historical retrospective data and significant prospective clinical trials.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.