Evidence map›Paper›PMID 26756474›Full record

ArticlePloS one2016

Complex and Conflicting Social Norms: Implications for Implementation of Future HIV Pre-Exposure Prophylaxis (PrEP) Interventions in Vancouver, Canada.

Rod Knight, Will Small, Anna Carson, Jean Shoveller

Abstract read
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rod KnightFaculty of Health Sciences, Simon Fraser University, Burnaby, Canada.
Will SmallFaculty of Health Sciences, Simon Fraser University, Burnaby, Canada.
Anna CarsonSchool of Population and Public Health, University of British Columbia, Vancouver, Canada.
Jean ShovellerSchool of Population and Public Health, University of British Columbia, Vancouver, Canada.

Funding

Vancouver Drug Users Study: The Impacts of Evolving Drug Use Patterns on HIV/AIDSU01DA038886 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI DEBECK, KORA, HAYASHI, KANNA · 2015 to 2024
$12.1M
Initiation of injection drug use and HIV risks among street-involved youthR01DA028532 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI WOOD, EVAN · 2010 to 2014
$1.9M
HIV Risk Environments among FSW and DU: A Longitudinal Ethno-Spatial ApproachR01DA033147 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI KERR, THOMAS, SHANNON, KATE · 2012 to 2016
$1.8M
Canadian Institutes of Health Research EPP-122906Canadian Institutes of Health Research HHP-123778NIDA NIH HHS R01 DA028532NIDA NIH HHS R01DA028532NIDA NIH HHS R01 DA033147NIDA NIH HHS R01DA033147NIDA NIH HHS U01 DA038886NIDA NIH HHS U01DA038886
6 · The paper itself

Abstract

backgroundHIV Pre-Exposure Prophylaxis (PrEP) has been found to be efficacious in preventing HIV acquisition among seronegative individuals in a variety of risk groups, including men who have sex with men and people who inject drugs. To date, however, it remains unclear how socio-cultural norms (e.g., attitudes towards HIV; social understandings regarding HIV risk practices) may influence the scalability of future PrEP interventions. The objective of this study is to assess how socio-cultural norms may influence the implementation and scalability of future HIV PrEP interventions in Vancouver, Canada.

methodsWe conducted 50 interviews with young men (ages 18-24) with a variety of HIV risk behavioural profiles (e.g., young men who inject drugs; MSM). Interviews focused on participants' experiences and perceptions with various HIV interventions and policies, including PrEP.

resultsWhile awareness of PrEP was generally low, perceptions about the potential personal and public health gains associated with PrEP were interconnected with expressions of complex and sometimes conflicting social norms. Some accounts characterized PrEP as a convenient form of reliable protection against HIV, likening it to the female birth control pill. Other accounts cast PrEP as a means to facilitate 'socially unacceptable' behaviour (e.g., promiscuity). Stigmatizing rhetoric was used to position PrEP as a tool that could promote some groups' proclivities to take 'risks'.

conclusionStigma regarding 'risky' behaviour and PrEP should not be underestimated as a serious implementation challenge. Pre-implementation strategies that concomitantly aim to improve knowledge about PrEP, while addressing associated social prejudices, may be key to effective implementation and scale-up.

Indexed as

Pre-Exposure ProphylaxisSocial NormsCanadaDemographyHealth Planning GuidelinesHIV InfectionsHumansMaleYoung Adult

Identifiers

PMID26756474
PMCPMC4710521

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.