ArticleOtology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology2016
Cortical Plasticity and Reorganization in Pediatric Single-sided Deafness Pre- and Postcochlear Implantation: A Case Study.
Article in Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
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Who cites it
50 citing papers in PubMed, 110 citations in OpenAlex.
- Neuronal mechanisms underlying binaural performance with cochlear implant in single-sided deafness: a [European journal of nuclear medicine and molecular imaging · 2026Article
- Ten years of research on the sound quality of cochlear implants.Frontiers in human neuroscience · 2026Review
- Article
- A digital audio workstation approach for matching the sound quality of speech and music for single-sided deaf patients fit with cochlear implants.Frontiers in neuroscience · 2026Article
- Long-Term Results in Cochlear Implantation in Single-Sided Deafness in Children and Adult Populations.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2025Observational
- Visual Reliance in Severe Hearing Loss: Visual Evoked Potentials (VEPs) Study.Audiology research · 2025Article
- Cochlear implantation for children with single-sided deafness: parents' perspectives.Journal of the Royal Society of New Zealand · 2025Article
- Somatosensory cross-modal activation and changes in cortical somatosensory evoked potential responses in single-sided deafness: an EEG study.Frontiers in neuroscience · 2025Article
- Validation of direct recording of electrically evoked cortical auditory evoked potentials through a cochlear implant system.Scientific reports · 2024Article
- Neurocognitive outcomes in young adults with cochlear implants: The role of early language access and crossmodal plasticity.Hearing research · 2024Article
- Cochlear Implantation Outcomes in Pediatric Unilateral Hearing Loss: Impact of Device Use and Direct Input.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2024Article
- Do Otologists and Other Otolaryngologists Manage Single-Sided Deafness Differently?The journal of international advanced otology · 2024Article
- Cochlear Implantation in Children Affected by Single-Sided Deafness: A Comprehensive Review.Audiology research · 2024Review
- Person-centered aural rehabilitation program improved mood, cognition, and auditory processing in a professional musician who uses a hearing aid and cochlear implant: Case Report.Frontiers in rehabilitation sciences · 2024Article
- Electrically evoked late latency response using single electrode stimulation and its relation to speech perception among paediatric cochlear implant users.Frontiers in human neuroscience · 2024Article
- Bidirectional remodeling of the central auditory system caused by unilateral auditory deprivation.Frontiers in neurology · 2024Review
- Effects of cochlear implantation on cognitive decline in older adults: A systematic review and meta-analysis.Heliyon · 2023Article
- Health-Related Quality of Life in Children With Unilateral Sensorineural Hearing Loss Following Cochlear Implantation.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2023Article
- Crossmodal plasticity in hearing loss.Trends in neurosciences · 2023Review
- A cortical biomarker of audibility and processing efficacy in children with single-sided deafness using a cochlear implant.Scientific reports · 2023Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
hypothesisThe purpose of this study was to examine changes in cortical development and neuroplasticity in a child with single-sided deafness (SSD) before and after cochlear implantation (CI).
backgroundThe extent to which sensory pathways reorganize in childhood SSD is not well understood and there is currently little evidence demonstrating the efficacy of CI in children with SSD.
methodsHigh-density 128-channel electroencephalography (EEG) was used to collect cortical auditory evoked potentials (CAEP), cortical visual evoked potentials (CVEP), and cortical somatosensory evoked potentials (CSSEP) in a child with SSD, pre-CI and at subsequent sessions until approximately 3 years post-CI in her right ear which occurred at age 9.86 years. Behavioral correlates of speech perception and sound localization were also measured.
resultsPre-CI, high-density EEG showed evidence of delayed auditory cortical response morphology, auditory cortical development strongly contralateral (to the normal hearing ear), evidence of increased cognitive load, and cross-modal reorganization by the visual and somatosensory modalities. The post-CI developmental trajectory provided clear evidence of age-appropriate development of auditory cortical responses, and decreased cross-modal reorganization, consistent with improved speech perception and sound localization.
conclusionPost-CI, the child demonstrated age-appropriate auditory cortical development and improved speech perception and sound localization suggestive of significant benefits from cochlear implantation. Reversal of somatosensory recruitment was clearly apparent, and only a residual amount of visual cross-modal plasticity remained postimplantation. Overall, our results suggest that CI in pediatric SSD patients may benefit from a highly plastic cortex in childhood.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.