ArticleEnvironmental science & technology2016
Response of Simulated Drinking Water Biofilm Mechanical and Structural Properties to Long-Term Disinfectant Exposure.
Article in Environmental science & technology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Isoferulic acid suppressesFrontiers in microbiology · 2026Article
- Flagellum-driven motility enhancesApplied and environmental microbiology · 2025Article
- Diverse reactions of aquaculture biofilter biofilms following acute high-dose peracetic acid.Biofilm · 2025Article
- Texture-based speciation of otitis media-related bacterial biofilms from optical coherence tomography images using supervised classification.Journal of biophotonics · 2024Article
- Application of Calcium Hypochlorite for Sanitizing 3/16-Inch Tubing Used in Maple Sap Collection.Microorganisms · 2024Article
- Impact of operational conditions on drinking water biofilm dynamics and coliform invasion potential.Applied and environmental microbiology · 2024Article
- Influence of phosphate on bacterial release from activated carbon point-of-use filters and on biofilm characteristics.The Science of the total environment · 2024Article
- Microfluidic investigation of the impacts of flow fluctuations on the development of Pseudomonas putida biofilms.NPJ biofilms and microbiomes · 2023Article
- Effects of phosphate and silicate on stiffness and viscoelasticity of mature biofilms developed with simulated drinking water.Biofouling · 2023Article
- Antibiofilm and Antiquorum Sensing Potential ofFoods (Basel, Switzerland) · 2022Article
- Effect of Nonphosphorus Corrosion Inhibitors on Biofilm Pore Structure and Mechanical Properties.Environmental science & technology · 2020Article
- Bacterial Density and Biofilm Structure Determined by Optical Coherence Tomography.Scientific reports · 2019Article
- Dynamics of the physiochemical and community structures of biofilms under the influence of algal organic matter and humic substances.Water research · 2019Article
- Characterization of Mixed-Species Biofilm Formed byFrontiers in microbiology · 2019Article
- Effect of divalent ions and a polyphosphate on composition, structure, and stiffness of simulated drinking water biofilms.NPJ biofilms and microbiomes · 2018Article
- Long-Term Effects of Residual Chlorine onFrontiers in microbiology · 2018Article
- Disintegration of simulated drinking water biofilms with arrays of microchannel plasma jets.NPJ biofilms and microbiomes · 2018Article
- Effect of temperature and colonization of Legionella pneumophila and Vermamoeba vermiformis on bacterial community composition of copper drinking water biofilms.Microbial biotechnology · 2017Article
- Removal of Foodborne Pathogen Biofilms by Acidic Electrolyzed Water.Frontiers in microbiology · 2017Article
- Investigating the role of biofilms in trihalomethane formation in water distribution systems with a multicomponent model.Water research · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
Mechanical and structural properties of biofilms influence the accumulation and release of pathogens in drinking water distribution systems (DWDS). Thus, understanding how long-term residual disinfectants exposure affects biofilm mechanical and structural properties is a necessary aspect for pathogen risk assessment and control. In this study, elastic modulus and structure of groundwater biofilms was monitored by atomic force microscopy (AFM) and optical coherence tomography (OCT) during three months of exposure to monochloramine or free chlorine. After the first month of disinfectant exposure, the mean stiffness of monochloramine- or free-chlorine-treated biofilms was 4 to 9 times higher than those before treatment. Meanwhile, the biofilm thickness decreased from 120 ± 8 μm to 93 ± 6-107 ± 11 μm. The increased surface stiffness and decreased biofilm thickness within the first month of disinfectant exposure was presumably due to the consumption of biomass. However, by the second to third month during disinfectant exposure, the biofilm mean stiffness showed a 2- to 4-fold decrease, and the biofilm thickness increased to 110 ± 7-129 ± 8 μm, suggesting that the biofilms adapted to disinfectant exposure. After three months of the disinfectant exposure process, the disinfected biofilms showed 2-5 times higher mean stiffness (as determined by AFM) and 6-13-fold higher ratios of protein over polysaccharide, as determined by differential staining and confocal laser scanning microscopy (CLSM), than the nondisinfected groundwater biofilms. However, the disinfected biofilms and nondisinfected biofilms showed statistically similar thicknesses (t test, p > 0.05), suggesting that long-term disinfection may not significantly remove net biomass. This study showed how biofilm mechanical and structural properties vary in response to a complex DWDS environment, which will contribute to further research on the risk assessment and control of biofilm-associated-pathogens in DWDS.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.