Evidence map›Paper›PMID 26755643›Full record

ArticleThe British journal of ophthalmology2016

Wide field of view swept-source optical coherence tomography for peripheral retinal disease.

Ryan P McNabb, Dilraj S Grewal, Rajvi Mehta, Stefanie G Schuman, Joseph A Izatt, Tamer H Mahmoud, Glenn J Jaffe, Prithvi Mruthyunjaya, Anthony N Kuo

Open access · greenAbstract readComparative Study
In one paragraph

Article in The British journal of ophthalmology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 61 citations in OpenAlex.

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  4. Peripheral retinal and choroidal thickness of eyes with reticular pseudodrusen.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ryan P McNabbDuke Eye Center, Duke University School of Medicine, Durham, North Carolina, USA.
Dilraj S GrewalDuke Eye Center, Duke University School of Medicine, Durham, North Carolina, USA.
Rajvi MehtaDuke Eye Center, Duke University School of Medicine, Durham, North Carolina, USA.
Stefanie G SchumanDuke Eye Center, Duke University School of Medicine, Durham, North Carolina, USA.
Joseph A IzattDuke Eye Center, Duke University School of Medicine, Durham, North Carolina, USA Department of Biomedical Engineering, Duke University, Durham, North Carolina, USA.
Tamer H MahmoudDuke Eye Center, Duke University School of Medicine, Durham, North Carolina, USA.
Glenn J JaffeDuke Eye Center, Duke University School of Medicine, Durham, North Carolina, USA.
Prithvi MruthyunjayaDuke Eye Center, Duke University School of Medicine, Durham, North Carolina, USA.
Anthony N KuoDuke Eye Center, Duke University School of Medicine, Durham, North Carolina, USA.
Duke University · US

Funding

Intraoperative OCT Guidance of Intraocular SurgeryR01EY023039 · NEI · DUKE UNIVERSITY · PI IZATT, JOSEPH A, TOTH, CYNTHIA ANN · 2013 to 2016
$3.9M
Whole Eye Optical Coherence Tomography to Improve Refractive Surgery and Eye CareR01EY024312 · NEI · DUKE UNIVERSITY · PI KUO, ANTHONY NANLIN · 2015 to 2024
$3.5M
NEI NIH HHS R01 EY023039NEI NIH HHS R01 EY024312
6 · The paper itself

Abstract

BACKGROUND/

aimsTo assess peripheral retinal lesions and the posterior pole in single widefield optical coherence tomography (OCT) volumes.

methodsA wide field of view (FOV) swept-source OCT (WFOV SSOCT) system was developed using a commercial swept-source laser and a custom sample arm consisting of two indirect ophthalmic lenses. Twenty-seven subjects with peripheral lesions (choroidal melanomas, choroidal naevi, sclerochoroidal calcification, retinitis pigmentosa, diabetic retinopathy, retinoschisis and uveitis) were imaged with the WFOV SSOCT. Volumes were taken in primary gaze. Using the optic nerve to fovea distance as a reference measurement, comparisons were made between the lateral FOV of the WFOV SSOCT, current generation spectral-domain OCT (SDOCT) and widefield scanning laser ophthalmoscopy (SLO) of the same eyes.

resultsPeripheral pathologies were captured with WFOV SSOCT in 26 of the 27 subjects. The one not captured was in the far nasal periphery and was not seen in the primary gaze volume. Posterior pole associated pathologies were captured in all subjects. Current generation SDOCT had a mean lateral FOV of 2.08±0.21 optic nerve to fovea distance units, WFOV SSOCT had an FOV of 4.62±0.62 units and SLO had an FOV of 9.35±1.02 units.

conclusionsWFOV OCT can be used to examine both peripheral retinal pathology and the posterior pole within a single volume acquisition. SLO had the greatest FOV, but does not provide depth information. Future studies using widefield OCT systems will help further delineate the role of WFOV OCT to quantitatively assess and monitor peripheral retinal disease in three dimensions.

Indexed as

FemaleHumansImaging, Three-DimensionalMaleMiddle AgedReproducibility of ResultsRetinaRetinal DiseasesTomography, Optical CoherenceImagingRetina

Identifiers

PMID26755643
PMCPMC5088499
OpenAlexW2233766655

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.