ArticleProceedings of the National Academy of Sciences of the United States of America2016
Testing the kinship theory of intragenomic conflict in honey bees (Apis mellifera).
Article in Proceedings of the National Academy of Sciences of the United States of America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 80 citations in OpenAlex.
- Genome Evolution in Social Insects.Genome biology and evolution · 2026Review
- Intracellular competition shapes plasmid population dynamics.Science (New York, N.Y.) · 2025Article
- Honey bee queen pheromone provides an early warning system to prevent collapsing colonies.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Intragenomic conflict associated with extreme phenotypic plasticity in queen-worker caste determination in honey bees (Apis mellifera).Genome biology · 2025Article
- Molecular Basis of Eusocial Complexity: The Case of Worker Reproductivity in Bees.Genome biology and evolution · 2024Article
- Lack of paternal silencing and ecotype-specific expression in head and body lice hybrids.Evolution letters · 2024Article
- Examining parent-of-origin effects on transcription and RNA methylation in mediating aggressive behavior in honey bees (Apis mellifera).BMC genomics · 2023Article
- Abundant small RNAs in the reproductive tissues and eggs of the honey bee, Apis mellifera.BMC genomics · 2022Article
- Sex-biased demography modulates male harm across the genome.Proceedings. Biological sciences · 2021Article
- Recombination mapping of the Brazilian stingless bee Frieseomelitta varia confirms high recombination rates in social hymenoptera.BMC genomics · 2021Article
- How does epigenetics influence the course of evolution?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Article
- Parent-of-origin effects, allele-specific expression, genomic imprinting and paternal manipulation in social insects.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
- Males That Silence Their Father's Genes: Genomic Imprinting of a Complete Haploid Genome.Molecular biology and evolution · 2021Article
- Lack of parent-of-origin effects in Nasonia jewel wasp: A replication and extension study.PloS one · 2021Article
- Parent of origin gene expression in the bumblebee,Evolution letters · 2020Article
- Lineage and Parent-of-Origin Effects in DNA Methylation of Honey Bees (Apis mellifera) Revealed by Reciprocal Crosses and Whole-Genome Bisulfite Sequencing.Genome biology and evolution · 2020Article
- Bumblebee Workers Show Differences in Allele-Specific DNA Methylation and Allele-Specific Expression.Genome biology and evolution · 2020Article
- Unique DNA Methylation Profiles Are Associated with cis-Variation in Honey Bees.Genome biology and evolution · 2019Article
- Sociality emerges from solitary behaviours and reproductive plasticity in the orchid bee Euglossa dilemma.Proceedings. Biological sciences · 2019Article
- Comparative transcriptomics of social insect queen pheromones.Nature communications · 2019Article
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sexual reproduction brings genes from two parents (matrigenes and patrigenes) together into one individual. These genes, despite being unrelated, should show nearly perfect cooperation because each gains equally through the production of offspring. However, an individual's matrigenes and patrigenes can have different probabilities of being present in other relatives, so kin selection could act on them differently. Such intragenomic conflict could be implemented by partial or complete silencing (imprinting) of an allele by one of the parents. Evidence supporting this theory is seen in offspring-mother interactions, with patrigenes favoring acquisition of more of the mother's resources if some of the costs fall on half-siblings who do not share the patrigene. The kinship theory of intragenomic conflict is little tested in other contexts, but it predicts that matrigene-patrigene conflict may be rife in social insects. We tested the hypothesis that honey bee worker reproduction is promoted more by patrigenes than matrigenes by comparing across nine reciprocal crosses of two distinct genetic stocks. As predicted, hybrid workers show reproductive trait characteristics of their paternal stock, (indicating enhanced activity of the patrigenes on these traits), greater patrigenic than matrigenic expression, and significantly increased patrigenic-biased expression in reproductive workers. These results support both the general prediction that matrigene-patrigene conflict occurs in social insects and the specific prediction that honey bee worker reproduction is driven more by patrigenes. The success of these predictions suggests that intragenomic conflict may occur in many contexts where matrigenes and patrigenes have different relatednesses to affected kin.
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