ArticleThe American journal of tropical medicine and hygiene2016
Clinical and Environmental Surveillance for Vibrio cholerae in Resource Constrained Areas: Application During a 1-Year Surveillance in the Far North Region of Cameroon.
Article in The American journal of tropical medicine and hygiene, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 76 citations in OpenAlex.
- Estimating the proportion of clinically suspected cholera cases that are true Vibrio cholerae infections: A systematic review and meta-analysis.PLoS medicine · 2023Pooled it
- Cholera diagnosis in human stool and detection in water: A systematic review and meta-analysis.PloS one · 2022Pooled it
- Article
- Environmental surveillance of pathogens in Africa.Applied and environmental microbiology · 2026Review
- A colorimetric method for detecting virulent bacteriophage to Vibrio cholerae in fecal and environmental samples.PLoS neglected tropical diseases · 2025Article
- Cholera rapid diagnostic tests at the host-microbe interface: Key Considerations for Global Deployments.medRxiv : the preprint server for health sciences · 2025Article
- Enhancing national cholera surveillance using rapid diagnostic tests (RDTs): A mixed methods evaluation.PLoS neglected tropical diseases · 2025Article
- Non-O1/O139 environmental Vibrio cholerae from Northern Cameroon reveals potential intra-/inter-continental transmissions.PLoS neglected tropical diseases · 2025Article
- Epidemiologic and Genomic Surveillance of Vibrio cholerae and Effectiveness of Single-Dose Oral Cholera Vaccine, Democratic Republic of the Congo.Emerging infectious diseases · 2025Article
- Can Wastewater Surveillance Enhance Genomic Tracking of Climate-Driven Pathogens?Microorganisms · 2025Review
- Effectiveness of a single dose of oral cholera vaccine: findings from epidemiological and genomic surveillance ofmedRxiv : the preprint server for health sciences · 2024Article
- Attitude towards cholera vaccination and its related factors in Jordan amid the 2022 Middle East outbreak.BMC public health · 2024Article
- Effectiveness of one dose of killed oral cholera vaccine in an endemic community in the Democratic Republic of the Congo: a matched case-control study.The Lancet. Infectious diseases · 2024Article
- Cholera Deaths During Outbreaks in Uvira, Eastern Democratic Republic of the Congo, 10-35 Months After Mass Vaccination.Open forum infectious diseases · 2024Article
- Review of Rapid Diagnostic Methods forThe East African health research journal · 2023Article
- Development of a Monoclonal Antibody to a Vibriophage as a Proxy for Vibrio cholerae Detection.Infection and immunity · 2022Article
- Article
- Cholera rapid diagnostic tests recycled for PCR confirmation.The Lancet. Global health · 2022Article
- Contrasting Epidemiology of Cholera in Bangladesh and Africa.The Journal of infectious diseases · 2021Review
- Clinical Cholera Surveillance Sensitivity in Bangladesh and Implications for Large-Scale Disease Control.The Journal of infectious diseases · 2021Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biological confirmation of the presence of Vibrio cholerae in clinical and environmental samples is often constrained due to resource- and labor-intensive gold standard methods. To develop low-cost, simple, and sustainable surveillance techniques, we modified previously published specimen sampling and culture techniques and applied the use of enriched dipstick testing in conjunction with the use of filter paper for DNA specimen preservation during clinical and environmental surveillance in the Far North of Cameroon from August 2013 to October 2014. The enriched dipstick methodology during routine use in a remote setting demonstrated a specificity of 99.8% compared with polymerase chain reaction (PCR). The novel application of filter paper as a preservation method for cholera DNA specimens reduced the need for cold chain storage and allowed for PCR characterization and confirmation of V. cholerae. The application of basic technologies such as the enriched dipstick, the use of simplified gauze filtration for environmental sample collection, and the use of filter paper for sample preservation enabled early case identification with reduced logistics and supply cost while reporting minimal false-positive results. Simplified laboratory and epidemiological methodologies can improve the feasibility of cholera surveillance in rural and resource-constrained areas, facilitating early case detection and rapid response implementation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.