Evidence map›Paper›PMID 26754931›Full record

ArticleSleep & breathing = Schlaf & Atmung2016

Oral appliance in sleep apnea treatment: respiratory and clinical effects and long-term adherence.

Patrick Bachour, Adel Bachour, Paula Kauppi, Paula Maasilta, Antti Mäkitie, Tuula Palotie

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Evolution of adherence and self-reported symptoms over 36 months with mandibular advancement device therapy for obstructive sleep apnea: a retrospective study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
    Article
  4. Article
  5. Review
  6. Asthma and Three Colinear Comorbidities: Obesity, OSA, and GERD.The journal of allergy and clinical immunology. In practice · 2021
    Review
  7. Asthma and Obstructive Sleep Apnea Overlap: What Has the Evidence Taught Us?American journal of respiratory and critical care medicine · 2020
    Review
  8. Review
  9. Predicting Success of Oral Appliance Therapy in Treating Obstructive Sleep Apnea Using Drug-Induced Sleep Endoscopy.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2018
    Article
  10. Diagnosis and treatment of obstructive sleep apnea in adults.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2017
    Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Patrick BachourHeart and Lung Center, Sleep Unit, University of Helsinki and Helsinki University Hospital, P.O.BOX 160, FI-00029, HUS Helsinki, Finland. patrick.bachour@helsinki.fi.
Adel BachourHeart and Lung Center, Sleep Unit, University of Helsinki and Helsinki University Hospital, P.O.BOX 160, FI-00029, HUS Helsinki, Finland.
Paula KauppiInflammation Center, Allergy Department, University of Helsinki and Helsinki University Hospital, P.O.BOX 160, FI-00029, HUS Helsinki, Finland.
Paula MaasiltaHeart and Lung Center, Sleep Unit, University of Helsinki and Helsinki University Hospital, P.O.BOX 160, FI-00029, HUS Helsinki, Finland.
Antti MäkitieDepartment of Otorhinolaryngology - Head and Neck Surgery, University of Helsinki and Helsinki University Hospital, P.O.BOX 160, FI-00029, HUS Helsinki, Finland.
Tuula PalotieDepartment of Oral and Maxillofacial Diseases, University of Helsinki, Helsinki, Finland.
University of Helsinki · FIHelsinki University Hospital · FIKarolinska Institutet · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThere is an increasing tendency to use oral appliance (OA) as an alternative treatment for sleep apnea. Here we report the long-term adherence and clinical effects of OA therapy.

methodsAll sleep apnea patients treated at the Department of Dentistry between the years 2006 and 2013 (n = 1208) were reviewed. A questionnaire about OA adherence, asthma symptoms (Asthma Control Test™, ACT), and general health was sent to all patients who continued OA therapy after the 1-month follow-up visit (n = 811). OA was adjusted to obtain at least 70 % of the maximal protrusion of the mandible.

resultsThe response rate was 37.4 % (99 women, 204 men). The mean ± SD age and BMI were 58.7 ± 10.3 years and 27.3 ± 4.0 kg/m(2), respectively. During the mean follow-up period of 3.3 years, there was no significant variation in BMI. Forty-one patients abandoned OA therapy yielding an adherence rate of 86 %. Ninety-seven percent of patients used OA ≥4 h/day, and the mean daily use was 7.2 ± 1.1 h. The ACT score improved with OA use from 16.0 ± 5.9 to 20.1 ± 3.8 (p = 0.004), indicating better asthma control. The apnea and hypopnea index decreased significantly from 27 ± 19 at baseline to 10 ± 10 with OA therapy (p = 0.001).

conclusionsAfter a 1-month trial period, the long-term adherence to oral appliance was good. OA therapy decreased apneas and hypopneas significantly, and its long-term use was associated with an improvement in respiratory and asthma symptoms.

Indexed as

Occlusal SplintsPolysomnographyAdultAgedAsthmaComorbidityFemaleFollow-Up StudiesHumansLong-Term CareMaleMandibular AdvancementMiddle AgedPatient ComplianceSleep Apnea, ObstructiveSurveys and QuestionnairesAsthmaOral sleep apnea applianceQuestionnaireSleep study

Identifiers

PMID26754931
OpenAlexW2271292533

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.