ArticleBMC pediatrics2016
Seasonal variation in haematological and biochemical reference values for healthy young children in The Gambia.
Article in BMC pediatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Haematological and Biochemical Reference Values for Healthy Population of Maferinyah Rural Community in Guinea.BioMed research international · 2020Trial
- Seasonal and sex-specific variations in haematological parameters in 4 to 5.5-month-old infants in Guinea-Bissau, West Africa.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2017Trial
- Seasonal variations in haematological and biochemical parameters of healthy Gambian adults: Retrospective study 2018-2022.PLOS global public health · 2024Article
- Complete Blood Count Reference Intervals for Children Aged Less Than 1 to 12 Years in the Northern Region of Ghana.BioMed research international · 2024Article
- Micronutrient Status and Other Correlates of Hemoglobin among Children with Stunting: A Cross-Sectional Study in Uganda.Nutrients · 2023Article
- Region-specific laboratory reference intervals are important: A systematic review of the data from Africa.PLOS global public health · 2022Article
- Comparison of Lymphocyte Subset Populations in Children From South Africa, US and Europe.Frontiers in pediatrics · 2020Article
- The Rough Guide to Monocytes in Malaria Infection.Frontiers in immunology · 2018Review
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundHaematological and biochemistry reference values for children are important for interpreting clinical and research results however, differences in demography and environment poses a challenge when comparing results. The study defines reference intervals for haematological and biochemistry parameters and examines the effect of seasonality in malaria transmission.
methodsBlood samples collected from clinically healthy children, aged 12-59 months, in two surveys during the dry and wet season in the Upper River region of The Gambia were processed and the data analysed to generate reference intervals based on the 2.5(th) and 97.5(th) percentiles of the data.
resultsAnalysis was based on data from 1141 children with median age of 32 months. The mean values for the total white cell count and differentials; lymphocyte, monocyte and neutrophil decreased with increasing age, were lower in males and higher in the wet season survey. However, platelet values declined with age (p < 0.0001). There was no evidence of effect of gender on mean values of AST, ALT, lymphocytes, monocytes, platelets and haemoglobin.
conclusionMean estimates for haematological and biochemistry reference intervals are affected by age and seasonality in the first five years of life. This consistency is important for harmonisation of reference values for clinical care and interpretation of trial results.
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Registered trials
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