Evidence map›Paper›PMID 26754573›Full record

ArticleScientific reports2016

Dissecting the influence of Neolithic demic diffusion on Indian Y-chromosome pool through J2-M172 haplogroup.

Sakshi Singh, Ashish Singh, Raja Rajkumar, Katakam Sampath Kumar, Subburaj Kadarkarai Samy, Sheikh Nizamuddin, Amita Singh, Shahnawaz Ahmed Sheikh, Vidya Peddada, Vinee Khanna and 5 more

Abstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Sakshi SinghCSIR-Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad, India.
Ashish SinghCSIR-Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad, India.
Raja RajkumarCSIR-Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad, India.
Katakam Sampath KumarCSIR-Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad, India.
Subburaj Kadarkarai SamyCSIR-Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad, India.
Sheikh NizamuddinCSIR-Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad, India.
Amita SinghCSIR-Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad, India.
Shahnawaz Ahmed SheikhCSIR-Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad, India.
Vidya PeddadaCSIR-Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad, India.
Vinee KhannaCSIR-Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad, India.
Pandichelvam VeeraiahCSIR-Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad, India.
Aridaman PanditTheoretical Biology and Bioinformatics, Utrecht University, Utrecht, Netherlands.
Gyaneshwer ChaubeyEvolutionary Biology Group, Estonian Biocentre, Tartu, Estonia.
Lalji SinghCSIR-Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad, India.
Kumarasamy ThangarajCSIR-Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global distribution of J2-M172 sub-haplogroups has been associated with Neolithic demic diffusion. Two branches of J2-M172, J2a-M410 and J2b-M102 make a considerable part of Y chromosome gene pool of the Indian subcontinent. We investigated the Neolithic contribution of demic dispersal from West to Indian paternal lineages, which majorly consists of haplogroups of Late Pleistocene ancestry. To accomplish this, we have analysed 3023 Y-chromosomes from different ethnic populations, of which 355 belonged to J2-M172. Comparison of our data with worldwide data, including Y-STRs of 1157 individuals and haplogroup frequencies of 6966 individuals, suggested a complex scenario that cannot be explained by a single wave of agricultural expansion from Near East to South Asia. Contrary to the widely accepted elite dominance model, we found a substantial presence of J2a-M410 and J2b-M102 haplogroups in both caste and tribal populations of India. Unlike demic spread in Eurasia, our results advocate a unique, complex and ancient arrival of J2a-M410 and J2b-M102 haplogroups into Indian subcontinent.

Indexed as

Chromosomes, Human, YGenetics, PopulationHaplotypesChromosomes, HumanGeographyHumansIndiaPhylogenyPhylogeography

Identifiers

PMID26754573
PMCPMC4709632

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