Evidence map›Paper›PMID 26754461›Full record

ArticleDevelopmental cognitive neuroscience2016

Considerations for MRI study design and implementation in pediatric and clinical populations.

Deanna J Greene, Kevin J Black, Bradley L Schlaggar

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Developmental cognitive neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05418608 (Novel in Vivo Synaptic Imaging in Experienced Meditators), which is not on this map. Cited by 78 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed, 1 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05418608 phase1completednot on this mapstarted 2022, after this paper: background citation

Novel in Vivo Synaptic Imaging in Experienced Meditators

TypeinterventionalSponsorYale UniversityRan2022 to 2024Enrolled40ConditionsBehavior, HealthArmsRadiotracer
3 · Its place in the literature

Who cites it

78 citing papers in PubMed, 1 synthesis or guideline pooled it, 140 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Article
  8. Considerations for conducting developmental neuroimaging research on mental health topics.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. The promise of precision functional mapping for neuroimaging in psychiatry.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. The Brain's Control Networks in Reading: Insights From Cross-Task Studies of Youth.Mind, brain and education : the official journal of the International Mind, Brain, and Education Society · 2023
    Article

18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Deanna J GreeneDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, United States; Department of Radiology, Washington University School of Medicine, St. Louis, MO, United States. Electronic address: greened@npg.wustl.edu.
Kevin J BlackDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, United States; Department of Radiology, Washington University School of Medicine, St. Louis, MO, United States; Department of Neurology, Washington University School of Medicine, St. Louis, MO, United States; Department of Neuroscience, Washington University School of Medicine, St. Louis, MO, United States.
Bradley L SchlaggarDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, United States; Department of Radiology, Washington University School of Medicine, St. Louis, MO, United States; Department of Neurology, Washington University School of Medicine, St. Louis, MO, United States; Department of Neuroscience, Washington University School of Medicine, St. Louis, MO, United States; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, United States.
Washington University in St. Louis · US

Funding

Washington University Intellectual and Developmental Disabilities Research Center-Administrative Down Syndrome SupplementU54HD087011 · NICHD · WASHINGTON UNIVERSITY · PI CONSTANTINO, JOHN N. · 2015 to 2019
$7.1M
Washington University Intellectual and Developmental Disabilities Research CenterP30HD062171 · NICHD · WASHINGTON UNIVERSITY · PI NEIL, JEFFREY J. · 2010 to 2014
$4.3M
DEVELOPMENT OF SKILLED READING: FMRI STUDIESR01HD057076 · NICHD · WASHINGTON UNIVERSITY · PI SCHLAGGAR, BRADLEY L · 2008 to 2012
$1.7M
Training New Investigators in Neuroimaging and in the Neuropsychiatry of MovementK24MH087913 · NIMH · WASHINGTON UNIVERSITY · PI BLACK, KEVIN J · 2010 to 2014
$818k
PREDICTING OUTCOME IN CHILDREN WITH TIC DISORDERS USING NEUROIMAGING DATAK01MH104592 · NIMH · WASHINGTON UNIVERSITY · PI GREENE, DEANNA JACQUELYN · 2014 to 2018
$723k
PREDICTING OUTCOME IN CHILDREN WITH NEW-ONSET TICS USING NEUROIMAGING DATAR21NS091635 · NINDS · WASHINGTON UNIVERSITY · PI BLACK, KEVIN J, SCHLAGGAR, BRADLEY L · 2015 to 2016
$419k
NICHD NIH HHS P30 HD062171NICHD NIH HHS R01 HD057076NICHD NIH HHS U54 HD087011NIMH NIH HHS K01 MH104592NIMH NIH HHS K24 MH087913NINDS NIH HHS R21 NS091635
6 · The paper itself

Abstract

Human neuroimaging, specifically magnetic resonance imaging (MRI), is being used with increasing popularity to study brain structure and function in development and disease. When applying these methods to developmental and clinical populations, careful consideration must be taken with regard to study design and implementation. In this article, we discuss two major considerations particularly pertinent to brain research in special populations. First, we discuss considerations for subject selection and characterization, including issues related to comorbid conditions, medication status, and clinical assessment. Second, we discuss methods and considerations for acquisition of adequate, useable MRI data. Given that children and patients may experience anxiety with the scanner environment, preventing participation, and that they have a higher risk of motion artifact, resulting in data loss, successful subject compliance and data acquisition are not trivial tasks. We conclude that, as researchers, we must consider a number of issues when using neuroimaging tools to study children and patients, and we should thoughtfully justify our choices of methods and study design.

Indexed as

AnxietyArtifactsBrainBrain MappingChildHeadHumansMagnetic Resonance ImagingMental DisordersMovementPatient ComplianceDevelopmentInclusion/exclusion criteriaMock scannerMotion artifactNeuroimagingNeuropsychiatric disordersTourette syndrome

Identifiers

PMID26754461
PMCPMC4834255
OpenAlexW2209795071

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.