Trial reportLasers in medical science2016
The use of low-level laser therapy for controlling the gag reflex in children during intraoral radiography.
Trial report in Lasers in medical science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07509918 (Clinical Efficacy of Three Mucoadhesive Gels in Controlling Gag Reflex Among Children Aged 8-10 Years During Radiographic Examination), which is not on this map. Cited by 13 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Clinical Efficacy of Three Mucoadhesive Gels in Controlling Gag Reflex Among Children Aged 8-10 Years During Radiographic Examination:A Randomized Pilot Clinical Trial
Who cites it
13 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Gag reflex management in dental practice: a bibliometric analysis from 2000 to 2025.Frontiers in oral health · 2025Pooled it
- Effect of low-level laser stimulation of acupuncture points in pediatric dentistry: a systematic review.Lasers in medical science · 2023Pooled it
- Diagnostic efficacy of and indications for intraoral radiographs in pediatric dentistry: a systematic review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2020Pooled it
- Management of gag reflex for patients undergoing dental treatment.The Cochrane database of systematic reviews · 2019Pooled it
- Comparative effects of three mucoadhesive gels containing lidocaine, zinc acetate, and tannic acid on the gag reflex of dental patients: a randomized double-blind clinical trial.BMC oral health · 2024Trial
- Effectiveness of low-level laser therapy in reducing pain perception of children during dental local anesthetic administration using laser acupuncture pen on the LI4 point: a randomized clinical trial.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2023Trial
- The use of interactive distraction technique to manage gagging during impression taking in children: a single-blind, randomised controlled trial.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2021Trial
- Cleaning the palate and tongue without nausea: a mixed methods study exploring the appropriate depth and direction of oral care.BMC oral health · 2021Trial
- Role of photobiomodulation in controlling the gag reflex during posterior tooth extraction, a pilot case series.Lasers in medical science · 2026Article
- Effect of photo-bio-modulation on pain perception with inferior alveolar nerve block among children: A split mouth study.Bioinformation · 2025Article
- Application of Dental Lasers in the Field of Endodontics: A Review of Literature.Iranian endodontic journal · 2025Review
- An Overview about New Methods in Management of Gag Reflex during Dental Treatment: A Systematic Review.Journal of dentistry (Shiraz, Iran) · 2023Review
- Study Regarding the Optimal Dimension of Intraoral Bitewing Radiographs in Patients with Primary Dentition.International journal of environmental research and public health · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The current literature suggests that low-level laser stimulation of the PC 6 acupuncture points may prevent gagging. This study aimed to determine if low-level laser therapy (LLLT) can reduce the gag reflex in children undergoing intraoral maxillary radiography. This randomized, controlled, double-blind clinical trial was conducted with 25 children with moderate-to-very severe gag reflexes who required bilateral periapical radiographic examination of the maxillary molar region. Children's anxiety levels were initially evaluated using Corah's Dental Anxiety Scale (DAS) to identify any possible relationship between gagging and anxiety. A control radiograph was taken of one randomly selected side in each patient after simulated laser application so that the patient was blinded to the experimental conditions (control group). Laser stimulation was then performed for the experimental side. A laser probe was placed on the Pericardium 6 (PC 6) acupuncture point on each wrist, and laser energy was delivered for 14 s (300 mW, energy density 4 J/cm(2)) at a distance of 1 cm from the target tissue. Following laser stimulation, the experimental radiograph was taken (experimental group). Gagging responses were measured using the Gagging Severity Criteria for each group. Data were analyzed using Spearman's rho correlations and Mann-Whitney U tests. Both mean and median gagging scores were higher in the control group than in the experimental group. Patients who were unable to tolerate the intraoral control radiography were able to tolerate the procedure after LLLT. Differences between gagging scores of the control and experimental groups were statistically significant (P = .000). There was no significant correlation between gagging severity and anxiety score (P > .05). A negative correlation was found between age and gagging score in the control group (P ˂ .05). Within the limitations of this study, LLLT of the PC 6 acupuncture points appears to be a useful technique for controlling the gag reflex in children during maxillary radiography.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.