ArticleBMC pulmonary medicine2016
Association between personal exposure to ambient metals and respiratory disease in Italian adolescents: a cross-sectional study.
Article in BMC pulmonary medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Outdoor air pollutants and asthma risk in adolescents: evidence from a systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- Systemic inflammation mediates the relationship between urinary cadmium and chronic cough risk: findings based on multiple statistical models.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025Article
- Nickel removal from synthetic wastewater by novel zeolite-doped magnesium- iron- and zinc-oxide nanocomposites by hydrothermal-calcination technique.Scientific reports · 2024Article
- Exploring the link between the pediatric exposome, respiratory health, and executive function in children: a narrative review.Frontiers in public health · 2024Review
- Association between Exposure to Selected Heavy Metals and Blood Eosinophil Counts in Asthmatic Adults: Results from NHANES 2011-2018.Journal of clinical medicine · 2023Article
- Long-term PMEcotoxicology and environmental safety · 2022Article
- Association between prenatal metal exposure and adverse respiratory symptoms in childhood.Environmental research · 2022Article
- Critical windows of susceptibility in the association between manganese and neurocognition in Italian adolescents living near ferro-manganese industry.Neurotoxicology · 2021Article
- Assessment of Metal Concentrations and Associations with Pulmonary Function among Children with Asthma in Chicago, Illinois.International journal of environmental research and public health · 2021Article
- Dose-Response Relationship between Environmental Exposure to Nickel and Pulmonary Function in the Korean General Population Aged 40 or Older.International journal of environmental research and public health · 2021Article
- Maternal metal concentration during gestation and pediatric morbidity in children: an exploratory analysis.Environmental health and preventive medicine · 2021Article
- Association between selected urinary heavy metals and asthma in adults: a retrospective cross-sectional study of the US National Health and Nutrition Examination Survey.Environmental science and pollution research international · 2021Article
- Review of the effect of air pollution exposure from industrial point sources on asthma-related effects in childhood.Environmental epidemiology (Philadelphia, Pa.) · 2019Review
- Environmental exposure and health effects in a highly polluted area of Northern Italy: a narrative review.Environmental science and pollution research international · 2019Review
- An inhalation-ingestion bioaccessibility assay (IIBA) for the assessment of exposure to metal(loid)s in PMThe Science of the total environment · 2018Article
- Determinants of serum manganese levels in an Italian population.Molecular medicine reports · 2017Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundRelease of ambient metals during ferroalloy production may be an important source of environmental exposure for nearby communities and exposure to these metals has been linked to adverse respiratory outcomes. We sought to characterize the association between personal air levels of metals and respiratory health in Italian adolescents living in communities with historic and current ferroalloy activity.
methodsAs part of a study in the industrial province of Brescia, Italy, 410 adolescents aged 11-14 years were recruited. Participants were enrolled from three different communities with varying manganese (Mn) levels: Bagnolo Mella which has current ferroalloy activity, Valcamonica, which has historic ferroalloy activity and Garda Lake which has no history of ferroalloy activity. Particulate matter <10 μm in diameter (PM10) was collected for 24 h in filters using personal sampling. Mn, nickel (Ni), zinc (Zn), chromium (Cr) and iron (Fe) were measured in filters using x-ray fluorescence. Data on respiratory health was collected through questionnaire. Data for 280 adolescents were analyzed using a modified Poisson regression, and risk ratios were calculated for an interquartile (IQR) range increase in each pollutant.
resultsIn adjusted models including PM10 as a co-pollutant, we found significant associations between concentrations of Mn (RR: 1.09, 95% CI [1.00, 1.18] per 42 ng/m(3) increase), Ni (RR: 1.11, 95% CI [1.03, 1.21] per 4 ng/m(3) increase) and Cr (RR: 1.08, 95% CI [1.06, 1.11] per 9 ng/m(3) increase) and parental report of asthma. We also found significant associations between increased Mn and Ni and increased risk of asthma medication use in the past 12 months (RR: 1.13, 95% CI [1.04, 1.29] and (RR: 1.13, 95 % CI [1.01, 1.27] respectively).
conclusionsOur findings suggest that exposure to ambient Mn, Ni and Cr may be associated with adverse respiratory outcomes.
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