Evidence map›Paper›PMID 26753986›Full record

Trial reportThe Clinical neuropsychologist2016

Abbreviated Goal Management Training Shows Preliminary Evidence as a Neurorehabilitation Tool for HIV-associated Neurocognitive Disorders among Substance Users.

Kaitlin B Casaletto, David J Moore, Steven Paul Woods, Anya Umlauf, J C Scott, Robert K Heaton

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in The Clinical neuropsychologist, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Development of Goal Management TrainingFrontiers in psychiatry · 2022
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Cognition and addiction
.Dialogues in clinical neuroscience · 2019
    Review
  12. Everyday Multitasking Abilities in Older HIV+ Adults: Neurobehavioral Correlates and the Mediating Role of Metacognition.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2017
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Kaitlin B Casalettoa SDSU/UCSD Joint Doctoral Program in Clinical Psychology , San Diego , CA , USA.
David J Mooreb Department of Psychiatry , University of California , San Diego , CA , USA.
Steven Paul Woodsc Department of Psychology , University of Houston , Houston , TX , USA.
Anya Umlaufb Department of Psychiatry , University of California , San Diego , CA , USA.
J C Scottd Department of Psychiatry , University of Pennsylvania , Philadelphia , PA , USA.
Robert K Heatonb Department of Psychiatry , University of California , San Diego , CA , USA.
University of San Diego · USSan Diego State University · USUniversity of California, San Diego · USUniversity of Houston · USVA Healthcare-VISN 4 · US

Funding

STRUCTURAL NEUROIMAGING COREP30MH062512 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jennifer E Iudicello · 2001 to 2026
$50.4M
Translational Methamphetamine AIDS Research Center (TMARC)P50DA026306 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GRANT, IGOR · 2009 to 2018
$33.9M
A Metacognition-based Approach to Improve HAND Among Methamphetamine UsersF31DA035708 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CASALETTO, KAITLIN B · 2013 to 2015
$99k
Neural Response to Cognitive Overload in Posttraumatic Stress DisorderIK2CX000772 · VA · VA CONNECTICUT HEALTHCARE SYSTEM · PI SCOTT, JAMES COBB · 2012 to 2016
–
CSRD VA IK2 CX000772NIDA NIH HHS F31 DA035708NIDA NIH HHS F31-DA035708NIDA NIH HHS P50 DA026306NIMH NIH HHS P30 MH062512
6 · The paper itself

Abstract

objectiveSubstance use disorders are highly comorbid with and contribute to the increased prevalence of neurocognitive dysfunction observed in HIV infection. Despite their adverse impact on everyday functioning, there are currently no compensatory-based neurorehabilitation interventions validated for use among HIV+ substance users (HIV/SUD). This study examined the effectiveness of goal management training (GMT) alone or GMT as part of a metacognitive training among HIV/SUD individuals with executive dysfunction.

methodsNinety HIV/SUD individuals were randomized to a single 15-min session: (1) GMT (n = 30); (2) GMT plus metacognitive training (neurocognitive awareness; GMT + Meta; n = 30); or (3) active control (n = 30). Following a brief neurocognitive battery and study condition, participants performed a complex laboratory-based function task, Everyday Multitasking Test (Everyday MT), during which metacognition (awareness) was evaluated.

resultsThere was an increasing, but non-significant tendency for better Everyday MT performances across study conditions (Control ≤ GMT ≤ GMT + Meta; ps < .08). Post hoc analyses showed that GMT and GMT + Meta groups demonstrated small benefits (d = .20-.27) compared to the control arm but did not differ from one another (ds < .10). When GMT groups were combined, there were significant medium effect size benefits in Everyday MT performance and metacognitive task appraisals as compared to the control condition. Among participants who underwent GMT, benefits were most prominent in persons with poorer pre-training dual-tasking ability, depression, and methamphetamine use disorders (ds = .35-1.04).

conclusionsA brief compensatory strategy has benefits for everyday multitasking and metacognition among HIV+ substance users with executive dysfunction. Future work exploring more intensive trainings, potentially complimentary to other restorative approaches and/or pharmacological treatments, is warranted.

Indexed as

Executive FunctionGoalsNeurological RehabilitationAwarenessCognition DisordersFemaleHIV InfectionsHumansMaleMiddle AgedNeuropsychological TestsSubstance-Related DisordersActivities of daily livingAwarenessCompensatory strategies.Executive functions

Identifiers

PMID26753986
PMCPMC4801659
OpenAlexW2286037089

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.