Trial reportInternational orthopaedics2016
No differences between direct anterior and lateral approach for primary total hip arthroplasty related to muscle damage or functional outcome.
Trial report in International orthopaedics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02719236 (Direct Anterior Approach Versus Direct Lateral Approach in Cementless Total Hip Arthroplasty), which is not on this map. Cited by 41 papers, 12 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Direct Anterior Approach Versus Direct Lateral Approach in Cementless Total Hip Arthroplasty
Who cites it
41 citing papers in PubMed, 12 syntheses or guidelines pooled it, 88 citations in OpenAlex.
- Early clinical efficacy and safety of different surgical approaches in total hip arthroplasty: a systematic review and network meta-analysis.BMC musculoskeletal disorders · 2026Pooled it
- Comparative efficacy of direct anterior approach versus conventional surgical approaches in total hip arthroplasty: a systematic review and meta-analysis of randomized clinical trials.Journal of orthopaedic surgery and research · 2025Pooled it
- Postoperative Harris Hip Score Versus Harris Hip Score Difference in Hip Replacement: What to Report?Orthopaedic surgery · 2025Pooled it
- Pooled it
- Indirect comparisons of traction table versus standard table in total hip arthroplasty through direct anterior approach: a systematic review and frequentist network meta-analysis.Journal of orthopaedic surgery and research · 2024Pooled it
- Comparing direct anterior approach versus posterior approach or lateral approach in total hip arthroplasty: a systematic review and meta-analysis.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2023Pooled it
- Evaluation of Comparative Efficacy and Safety of Surgical Approaches for Total Hip Arthroplasty: A Systematic Review and Network Meta-analysis.JAMA network open · 2023Pooled it
- Serum biomarkers for the assessment of muscle damage in various surgical approaches in primary total hip arthroplasty: a systematic review of comparative studies.International orthopaedics · 2022Pooled it
- A meta-analysis on RCTs of direct anterior and conventional approaches in total hip arthroplasty.Scientific reports · 2021Pooled it
- Comparison of short-term outcomes between direct anterior approach (DAA) and SuperPATH in total hip replacement: a systematic review and network meta-analysis of randomized controlled trials.Journal of orthopaedic surgery and research · 2021Pooled it
- A systematic review and meta-analysis of the hip capsule innervation and its clinical implications.Scientific reports · 2021Pooled it
- Pooled it
- Platelet-rich plasma does not influence magnetic resonance imaging findings of the gluteus muscles after total hip arthroplasty through the Hardinge approach.Skeletal radiology · 2025Trial
- Trial
- Using the anterior capsule of the hip joint to protect the tensor fascia lata muscle during direct anterior total hip arthroplasty: a randomized prospective trial.BMC musculoskeletal disorders · 2020Trial
- Supercapsular percutaneously-assisted total hip (SuperPath) versus posterolateral total hip arthroplasty in bilateral osteonecrosis of the femoral head: a pilot clinical trial.BMC musculoskeletal disorders · 2019Trial
- Trial
- Transitioning to the direct anterior approach in total hip arthroplasty. Is it a true muscle sparing approach when performed by a low volume hip replacement surgeon?International orthopaedics · 2017Trial
- Article
- The economical and reliable image free navigation system for acetabular cup implantation in total hip arthroplasty.Journal of clinical orthopaedics and trauma · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim was to compare the muscle damage and functional outcomes between patients who underwent total hip arthroplasty through a direct anterior (49 patients) or a lateral approach (50 patients).
methodsA randomized, controlled, prospective study. The study variables were muscle damage based on post-operative levels of serum markers (citokynes and acute phase reactants) and MRI, and Harris hip score.
resultsPost-operatively, there were significantly higher mean levels in the lateral group related to interleukin 6 and 8, and tumor necrosis factor-alpha up to fourth postoperative day. By MRI at six post-operative months, the fatty atrophy in the gluteus muscles was more in the lateral group, but similar in the other muscles. The mean thickness of the tensor fasciae latae was significantly lower in the anterior group. Functional outcome was similar between groups at three and 12 post-operative months.
conclusionsMuscle damage due to the surgical approach had no influence on functional outcome after three post-operative months. Both anterior and lateral approaches for THA are similarly safe and feasible, so the choice depends only on the preference and experience of the surgeon.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.