ArticleBMC complementary and alternative medicine2016
Antibacterial and antibiotic-modifying activities of three food plants (Xanthosoma mafaffa Lam., Moringa oleifera (L.) Schott and Passiflora edulis Sims) against multidrug-resistant (MDR) Gram-negative bacteria.
Article in BMC complementary and alternative medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Biological properties ofF1000Research · 2024Pooled it
- Multifaceted role of Moringa oleifera leaf extract as antimicrobial, growth enhancer and mitigator of salt stress in tomato seedlings.BMC plant biology · 2025Article
- Unveiling Therapeutic Powers of Indigenous Flora: Antimicrobial, Antioxidant, and Anticancer Properties ofPharmaceuticals (Basel, Switzerland) · 2025Article
- Article
- Plant-Based Diets and Phytochemicals in the Management of Diabetes Mellitus and Prevention of Its Complications: A Review.Nutrients · 2024Review
- Identification of plant based potential antifungal compounds against BMK-1 protein of Bipolaris oryzae using molecular docking approach.Scientific reports · 2024Article
- Chemical Compositions, Pharmacological Properties and Medicinal Effects of GenusPlants (Basel, Switzerland) · 2024Review
- Article
- Proximate Analysis ofInternational journal of molecular sciences · 2023Article
- Antibacterial and antibiotic-potentiation activity of the constituents from aerial part of Donella welwitshii (Sapotaceae) against multidrug resistant phenotypes.BMC complementary medicine and therapies · 2022Article
- Potential Applications ofAntibiotics (Basel, Switzerland) · 2021Review
- Prenylated Flavonoids and C-15 Isoprenoid Analogues with Antibacterial Properties from the Whole Plant ofMolecules (Basel, Switzerland) · 2021Article
- An Efflux Pumps Inhibitor Significantly Improved the Antibacterial Activity of Botanicals fromTheScientificWorldJournal · 2021Article
- Antimicrobial effect of different herbal plant extracts against different microbial population.Saudi journal of biological sciences · 2020Article
- Inhibition ofMolecules (Basel, Switzerland) · 2020Article
- Moringin, A Stable Isothiocyanate fromMolecules (Basel, Switzerland) · 2020Article
- Review
- Antibacterial efficacy ofVeterinary world · 2019Article
- Antibacterial and Antibiotic Modifying Potential of Crude Extracts, Fractions, and Compounds fromEvidence-based complementary and alternative medicine : eCAM · 2019Article
- Isothiocyanates: An Overview of Their Antimicrobial Activity against Human Infections.Molecules (Basel, Switzerland) · 2018Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe present study was designed to investigate the antibacterial activities of the methanol extract of three edible plants, namely Xanthosoma mafaffa, Moringa oleifera and Passiflora edulis and their synergistic effects with some commonly used antibiotics against MDR Gram-negative bacteria expressing active efflux pumps.
methodsBroth microdilution method was used to determine the minimum inhibitory concentrations (MICs) and the minimum bactericidal concentrations (MBCs) of the extracts, as well as those of antibiotics in association with the extracts.
resultsThe phytochemical test indicate that all tested crude extracts contained polyphenols, triterpenes and steroids whilst other phytochemical classes were selectively distributed. Extracts showed antibacterial activities with minimum inhibitory concentrations ranging from 128-1024 μg/mL on the majority of the 19 tested Gram-negative bacterial strains. Extract from the pericarp of P. edulis inhibited the growth of 89.5% of the 19 tested bacterial strains, the lowest minimal inhibitory concentration (MIC) value of 128 μg/mL being recorded against Escherichia coli AG100 strain. In the presence of Phenylalanine-Arginine β-Naphtylamide (PAβN)], an efflux pump inhibitor (EPI), the activity of the extract from X. mafaffa increased on 40% of tested strains. In combination with antibiotics, extracts of X. mafaffa, M. oleifera and pericarp of P. edulis showed synergistic effects with some antibiotics against more than 75% of the tested bacteria.
conclusionThe results of the present study indicate that the tested plants may be used in the treatment of bacterial infections including the multi-resistant bacteria.
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