Evidence map›Paper›PMID 26753777›Full record

ReviewMedical & biological engineering & computing2016

Implantable neurotechnologies: a review of micro- and nanoelectrodes for neural recording.

Anoop C Patil, Nitish V Thakor

Abstract readReview
PubMed Publisher
In one paragraph

Review in Medical & biological engineering & computing, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. In vivo microelectrode arrays for neuroscience.Nature reviews. Methods primers · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Fabrication and Validation of Sub-Cellular Carbon Fiber Electrodes.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2024
    Article
  12. Article
  13. Sixty years in service to international biomedical engineering community.Medical & biological engineering & computing · 2023
    Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. Spatio-temporal feature extraction in sensory electroneurographic signals.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Anoop C PatilDepartment of Electrical and Computer Engineering, Singapore Institute for Neurotechnology, National University of Singapore, Singapore, Singapore. anoopcpatilnus@gmail.com.
Nitish V ThakorDepartment of Electrical and Computer Engineering, Singapore Institute for Neurotechnology, National University of Singapore, Singapore, Singapore. sinapsedirector@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electrodes serve as the first critical interface to the biological organ system. In neuroprosthetic applications, for example, electrodes interface to the tissue for either signal recording or tissue stimulation. In this review, we consider electrodes for recording neural activity. Recording electrodes serve as wiretaps into the neural tissues, providing readouts of electrical activity. These signals give us valuable insights into the organization and functioning of the nervous system. The recording interfaces have also shown promise in aiding treatment of motor and sensory disabilities caused by neurological disorders. Recent advances in fabrication technology have generated wide interest in creating tiny, high-density electrode interfaces for neural tissues. An ideal electrode should be small enough and be able to achieve reliable and conformal integration with the structures of the nervous system. As a result, the existing electrode designs are being shrunk and packed to form small form factor interfaces to tissue. Here, an overview of the historic and state-of-the-art electrode technologies for recording neural activity is presented first with a focus on their development road map. The fact that the dimensions of recording electrode sites are being scaled down from micron to submicron scale to enable dense interfaces is appreciated. The current trends in recording electrode technologies are then reviewed. Current and future considerations in electrode design, including the use of inorganic nanostructures and biologically inspired or biocomapatible materials are discussed, along with an overview of the applications of flexible materials and transistor transduction schemes. Finally, we detail the major technical challenges facing chronic use of reliable recording electrode technology.

Indexed as

Man-Machine SystemsMicroelectrodesNanotechnologyProstheses and ImplantsAnimalsBrainHumansNeural interfacesNeural prosthesesNeural recordingNeural recording technologyRecording electrodes

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.