Evidence map›Paper›PMID 26753671›Full record

ArticleHerz2016

Association of monocyte/HDL-C ratio with SYNTAX scores in patients with stable coronary artery disease.

H Kundi, E Kiziltunc, M Cetin, H Cicekcioglu, Z G Cetin, G Cicek, E Ornek

Abstract readComparative StudyEvaluation Study
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In one paragraph

Article in Herz, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed.

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  14. Monocyte to HDL ratio may predict thrombosis in patients with mechanical mitral and aortic valve prosthesis.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

H KundiDepartment of Cardiology, Ankara Numune Education and Research Hospital, Ankara, Turkey. harunkundi@hotmail.com.
E KiziltuncDepartment of Cardiology, Ankara Numune Education and Research Hospital, Ankara, Turkey.
M CetinDepartment of Cardiology, Ankara Numune Education and Research Hospital, Ankara, Turkey.
H CicekciogluDepartment of Cardiology, Ankara Numune Education and Research Hospital, Ankara, Turkey.
Z G CetinDepartment of Cardiology, Ankara Numune Education and Research Hospital, Ankara, Turkey.
G CicekDepartment of Cardiology, Ankara Numune Education and Research Hospital, Ankara, Turkey.
E OrnekDepartment of Cardiology, Ankara Numune Education and Research Hospital, Ankara, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to investigate the relationship between monocyte count/high density lipoprotein cholesterol (HDL-C) ratio (MHR) and the severity of coronary atherosclerosis, as assessed by the SYNTAX score (SXscore), in patients with stable coronary artery disease (CAD) undergoing coronary angiography. MATERIALS AND

methodsA total of 428 patients were included in the study between March 2012 and February 2015. The SXscore was determined with baseline coronary angiography. An SXscore ≥ 23 was regarded as severe CAD by definition, and the patients were divided into two groups: those with low SXscores (< 23) and those with high SXscores (≥ 23).

resultsMHR and C-reactive protein (CRP) were significantly higher in patients with high SXscores (p < 0.001 and p < 0.001, respectively). Left ventricular ejection fraction (LVEF) was lower in the group with high MHR and high SXscores. The cutoff value of MHR that predicted a high SXscore was 24, with a sensitivity of 66 % and a specificity of 65.1 %.

conclusionTo the best of our knowledge, this is the first study in the literature showing that MHR is significantly associated with SXscores. Our results suggest that MHR can be used as a prognostic marker in patients with stable CAD, since it is an easily available and inexpensive test.

Indexed as

Severity of Illness IndexAngina, StableBiomarkersCholesterol, HDLCoronary Artery DiseaseFemaleHumansLeukocyte CountMaleMiddle AgedMonocytesReproducibility of ResultsSensitivity and SpecificityBiomarkersCholesterol, HDLAtherogenesisCholesterolEchocardiographyInflammationPlaque, atherosclerotic

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.