ArticleHead and neck pathology2016
Melanoma of the Oral Cavity: an Analysis of 46 New Cases with Emphasis on Clinical and Histopathologic Characteristics.
Article in Head and neck pathology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Mucosal Melanoma In Situ of the Oral Cavity: A Case Report and Systematic Review of the Literature.Turkish archives of otorhinolaryngology · 2022Pooled it
- Oral Melanoma: A South American Collaborative Series of 21 Cases.Head and neck pathology · 2026Article
- Epithelioid Sarcoma of the Oral Cavity: A Multi-institutional Clinicopathologic and Immunophenotypic Characterization of Five Cases and Comprehensive Literature Review.Head and neck pathology · 2026Review
- Survival impact of second primary cutaneous and non-cutaneous melanoma in melanoma survivors.Journal of the European Academy of Dermatology and Venereology : JEADV · 2026Article
- Mucosal Melanoma of the Head and Neck: A 45-Year Experience of a Tertiary Cancer Center.Cancers · 2026Article
- From Malaise to Oral Pain: A Case Report on Oral Mucosal Melanoma.Case reports in dentistry · 2026Article
- Oral Mucosal Melanoma In Situ Manifesting as Multiple Gingival Macules Around a Dental Implant-Based Prosthesis: A Case Report.Case reports in dentistry · 2026Article
- Mucosal Melanoma of the Oral Cavity: Prognostic Factors Influencing Patient Survival Outcomes.Journal of clinical medicine · 2025Review
- Oral Soft Tissue and Jawbone Sarcomas: A Retrospective Clinicopathologic Analysis of 128 Cases from Two Institutions and Comprehensive Literature Review.Head and neck pathology · 2025Review
- Primary Malignant Melanoma of the Oropharynx: A Rare Case of a Tonsillar Melanotic Lesion.Cureus · 2025Article
- Rare Head and Neck Cancers and Pathological Diagnosis Challenges: A Comprehensive Literature Review.Diagnostics (Basel, Switzerland) · 2024Review
- Differential Diagnosis of Pigmented Lesions in the Oral Mucosa: A Clinical Based Overview and Narrative Review.Cancers · 2024Review
- Top Ten Differentials to Mull Over for Head and Neck Myoepithelial Neoplasms.Head and neck pathology · 2023Review
- Top Ten Oncocytic Head and Neck Lesions to Contemplate.Head and neck pathology · 2023Review
- Pigmented Oral Lesions: A Multicenter Study.European journal of dentistry · 2022Article
- Factors Associated With Oral Cancer Adverse Outcome at the Rwanda Military Hospital, a Retrospective Cross-Sectional Study.Frontiers in oral health · 2022Article
- A Large Oral Melanoma: A Case Report of a Rare but Aggressive Malignancy.European journal of dentistry · 2021Article
- Primary melanoma of the oral cavity: A multi-institutional retrospective analysis in Brazil.Medicina oral, patologia oral y cirugia bucal · 2021Article
- A Rare Case of Oral Mucosal Amelanotic Melanoma in a 77-year-old Immunocompromised Man.The Journal of clinical and aesthetic dermatology · 2021Article
- Primary amelanotic melanoma of the mandibular gingiva.Archives of craniofacial surgery · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Melanoma of the oral cavity is a rare malignancy that carries a poor prognosis. We identified 46 new cases of both primary and metastatic melanoma to the oral cavity. Following IRB approval, these cases were obtained from the Oral Pathology Biopsy Service archives of the UF College of Dentistry (1994-2014), the UK College of Dentistry (1997-2015), and the UM Medical Center (1988-2015). All slides were reviewed. The location, age, race, gender, clinical impression, duration of lesion, histopathologic diagnosis, and histopathologic features were recorded. Cases from the facial skin and those with an ambiguous diagnosis were excluded. Forty-six cases fulfilled the inclusion criteria with 32 primary cases, 11 known metastases, and 3 cases where metastasis could not be excluded. The primary cases included a total of 20 females and 12 males with an average age of 66.7 (range 27-95), and the majority (80 %) of the patients were Caucasian when race was known. Twenty-two of the 32 primary cases (68.8 %) were located in the maxillary mucosa, 5 in the mandibular mucosa or bone, and 5 in other locations. The clinicians' impressions varied from benign fibrous growths to high grade malignancies. The histopathology varied widely among the cases, however two cell types predominated (often in combination): epithelioid cells (50.0 %) and spindle cells (50.0 %). Only 53.1 % demonstrated melanin pigmentation. Oral melanoma remains one of the most diverse clinical and histopathologic diagnoses. Better understanding of this neoplasm may promote earlier diagnosis and may lead to improved outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.