Evidence map›Paper›PMID 26753175›Full record

ArticleACS biomaterials science & engineering

Nanofibrous Snake Venom Hemostat.

Vivek A Kumar, Navindee C Wickremasinghe, Siyu Shi, Jeffrey D Hartgerink

Abstract read
In one paragraph

Article in ACS biomaterials science & engineering. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 60 citations in OpenAlex.

  1. Review
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  12. Functional Mining of theMolecules (Basel, Switzerland) · 2020
    Article
  13. Review
  14. Article
  15. Perspective on the Therapeutics of Anti-Snake Venom.Molecules (Basel, Switzerland) · 2019
    Review
  16. Review
  17. Article
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  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Vivek A KumarDepartments of Chemistry and Bioengineering, Rice University, 6100 Main Street, Houston, Texas 77030, United States.
Navindee C WickremasingheDepartments of Chemistry and Bioengineering, Rice University, 6100 Main Street, Houston, Texas 77030, United States.
Siyu ShiDepartments of Chemistry and Bioengineering, Rice University, 6100 Main Street, Houston, Texas 77030, United States.
Jeffrey D HartgerinkDepartments of Chemistry and Bioengineering, Rice University, 6100 Main Street, Houston, Texas 77030, United States.
Rice University · US

Funding

Self-assembling Peptide Nanofiber Hydrogels for Nerve RegenerationR01DE021798 · NIDCR · RICE UNIVERSITY · PI HARTGERINK, JEFFREY DALE · 2012 to 2021
$3.7M
Multidomain Peptides for Inflammation and Angiogenic Mediated Tissue RegenerationF32DE023696 · NIDCR · RICE UNIVERSITY · PI KUMAR, VIVEK · 2013 to 2015
$161k
NIDCR NIH HHS F32 DE023696NIDCR NIH HHS R01 DE021798
6 · The paper itself

Abstract

Controlling perioperative bleeding is of critical importance to minimize hemorrhaging and fatality. Patients on anticoagulant therapy such as heparin have diminished clotting potential and are at risk for hemorrhaging. Here we describe a self-assembling nanofibrous peptide hydrogel (termed SLac) that on its own can act as a physical barrier to blood loss. SLac was loaded with snake-venom derived Batroxobin (50

Indexed as

hemostasismultidomain peptideself-assemblysupramolecular chemistry

Identifiers

PMID26753175
PMCPMC4704453
OpenAlexW2339638396

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.