ArticleTobacco regulatory science2016
Impairment of Endothelial Function by Little Cigar Secondhand Smoke.
Article in Tobacco regulatory science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 15 citations in OpenAlex.
- Tobacco and marijuana induce adverse effects on cardiac function and platelet activity and reduce tissue preservation following myocardial infarction.American journal of physiology. Heart and circulatory physiology · 2026Article
- Annual U.S. healthcare expenditures attributable to cigar smoking between 2001 and 2018, overall and by payer.PloS one · 2025Article
- Impairment of Endothelial Function by Aerosol From Marijuana Leaf Vaporizers.Journal of the American Heart Association · 2023Article
- Impairment of Endothelial Function by Cigarette Smoke Is Not Caused by a Specific Smoke Constituent, but by Vagal Input From the Airway.Arteriosclerosis, thrombosis, and vascular biology · 2022Article
- Comparable Impairment of Vascular Endothelial Function by a Wide Range of Electronic Nicotine Delivery Devices.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2022Article
- JUUL and Combusted Cigarettes Comparably Impair Endothelial Function.Tobacco regulatory science · 2020Article
- Vascular endothelial function is impaired by aerosol from a single IQOS HeatStick to the same extent as by cigarette smoke.Tobacco control · 2018Article
- Little cigars and cigarillos: Affect and perceived relative harm among U.S. adults, 2015.Addictive behaviors · 2018Article
- Little Cigars are More Toxic than Cigarettes and Uniquely Change the Airway Gene and Protein Expression.Scientific reports · 2017Article
- Ultrasound Assessment of Flow-Mediated Dilation of the Brachial and Superficial Femoral Arteries in Rats.Journal of visualized experiments : JoVE · 2016Article
- One Minute of Marijuana Secondhand Smoke Exposure Substantially Impairs Vascular Endothelial Function.Journal of the American Heart Association · 2016Article
- Childhood Secondhand Smoke Exposure and Risk of Dementia, Alzheimer's Disease and Stroke in Adulthood: A Prospective Cohort Study.The journal of prevention of Alzheimer's diseaseArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
objectivesLittle cigars and cigarillos are gaining in popularity as cigarette use wanes, mainly due to relaxed regulatory standards that make them cheaper, easier to buy individually, and available in a variety of flavors not allowed in cigarettes. To address whether they should be regulated as strictly as cigarettes, we investigated whether little cigar secondhand smoke (SHS) decreases vascular endothelial function like that of cigarettes.
methodsWe exposed rats to SHS from little cigars, cigarettes, or chamber air, for 10 minutes and measured the resulting acute impairment of arterial flow-mediated dilation (FMD).
resultsSHS from both little cigars and cigarettes impaired FMD. Impairment was greater after exposure to little cigar SHS than by cigarette SHS relative to pre-exposure values, although the post-exposure FMD values were not significantly different from each other.
conclusionsExposure to little cigar SHS leads to impairment of FMD that is at least equal to that resulting from similar levels of cigarette SHS. Our findings support the need to prevent even brief exposure to little cigar SHS, and support tobacco control policies that regulate little cigars as strictly as cigarettes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.