ArticleMaxillofacial plastic and reconstructive surgery2015
Early effect of Botox-A injection into the masseter muscle of rats: functional and histological evaluation.
Article in Maxillofacial plastic and reconstructive surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- What Happened to Masticatory Muscles after Botulinum-Toxin-Type A Injection into Masseter: A Systematic Review.Aesthetic plastic surgery · 2026Pooled it
- Mitophagy in Botulinum Toxin Type A-Induced Muscle Atrophy.Oral diseases · 2026Article
- Ultrasound assessment of botulinum toxin-A (BOTOX) injection into adult Arabian dromedary camels' lips: efficacy in detection and localization.BMC veterinary research · 2025Article
- Effect of botulinum toxin type A on masticatory function and musculoskeletal structure in rabbits.Scientific reports · 2025Article
- Histomorphometric Changes of the Masseter Muscle of Rats After a Single Injection of Botulinum Toxin Type A.Aesthetic plastic surgery · 2024Article
- Surgery-first approach reduces the overall treatment time without damaging long-term stability in the skeletal class III correction: a preliminary study.Maxillofacial plastic and reconstructive surgery · 2021Article
- The effect of fixation plate use on bone healing during the reconstruction of mandibular defects.Journal of the Korean Association of Oral and Maxillofacial Surgeons · 2019Article
- Effect of the masseter muscle injection of botulinum toxin A on the mandibular bone growth of developmental rats.Maxillofacial plastic and reconstructive surgery · 2018Article
- Non-invasive different modalities of treatment for temporomandibular disorders: review of literature.Journal of the Korean Association of Oral and Maxillofacial Surgeons · 2018Review
- S100 and p65 expression are increased in the masseter muscle after botulinum toxin-A injection.Maxillofacial plastic and reconstructive surgery · 2016Article
- Apoptotic action of botulinum toxin on masseter muscle in rats: early and late changes in the expression of molecular markers.SpringerPlus · 2016Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe purpose of this study was to evaluate the change of food intake after different dosages of botulinum toxin A (BTX) injection in the animal model. Additionally, the dimensional and histological change at 14 days after BTX injection was also evaluated.
methodsThe comparative study was performed using the BTX injection model in rats (
resultsThe recovery of food intake in groups 2 and 3 decreased significantly compared with group 1 from day 2 to day 7 and day 9 after injection (
conclusionsBTX injection to the masseter muscle in rats demonstrated short food-intake-rate reduction with recovery until 10 days after injection. The thickness of the masseter muscle and MYH2 expression were significantly changed according to the injected dose of BTX.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.