Evidence map›Paper›PMID 26752637›Full record

Observational studyPloS one2016

Geographic Variations in Retention in Care among HIV-Infected Adults in the United States.

Peter F Rebeiro, Stephen J Gange, Michael A Horberg, Alison G Abraham, Sonia Napravnik, Hasina Samji, Baligh R Yehia, Keri N Althoff, Richard D Moore, Mari M Kitahata and 3 more

Abstract readObservational Study
In one paragraph

Observational study in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed.

  1. Trial
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  7. Projecting the Potential Clinical and Economic Impact of HIV Prevention Resource Reallocation in Tennessee.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Article
  8. Article
  9. Article
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  11. Article
  12. Article
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  15. Article
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  18. Measuring engagement in HIV care: Measurement invariance in three racial/ethnic patient groups.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2020
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Peter F RebeiroVanderbilt University School of Medicine, Nashville, Tennessee, United States of America.
Stephen J GangeJohns Hopkins University, Baltimore, Maryland, United States of America.
Michael A HorbergMid-Atlantic Permanente Research Institute, Kaiser Permanente Mid-Atlantic States, Rockville, Maryland, United States of America.
Alison G AbrahamJohns Hopkins University, Baltimore, Maryland, United States of America.
Sonia NapravnikUniversity of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Hasina SamjiBritish Columbia Centre for Excellence in HIV/AIDS, Vancouver, British Columbia, Canada.
Baligh R YehiaUniversity of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America.
Keri N AlthoffJohns Hopkins University, Baltimore, Maryland, United States of America.
Richard D MooreJohns Hopkins University, Baltimore, Maryland, United States of America.
Mari M KitahataUniversity of Washington School of Medicine, Seattle, Washington, United States of America.
Timothy R SterlingVanderbilt University School of Medicine, Nashville, Tennessee, United States of America.
Frank C CurrieroJohns Hopkins University, Baltimore, Maryland, United States of America.
North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD)

Funding

WOMEN'S HEALTH AGENDAU01AI038858 · NIAID · SOCIAL AND SCIENTIFIC SYSTEMS, INC. · PI BENSON, CONSTANCE ANN · 1996 to 2008
$157.5M
AIDS Clinical Trials Group NetworkU01AI068636 · NIAID · SOCIAL AND SCIENTIFIC SYSTEMS, INC. · PI KURITZKES, DANIEL R. · 2006 to 2010
$147.1M
UCSF CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTEUL1RR024131 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSTON, S. CLAIBORNE · 2006 to 2011
$111.2M
University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI Kenneth Sherr · 1988 to 2026
$104.9M
Unsolicited R24 for the CFAR-Network of Integrated Clinical Sciences, CNICSR24AI067039 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Michael S. Saag · 2006 to 2026
$99.4M
Virology CoreP30AI027763 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STEVEN Grant DEEKS · 1988 to 2026
$93.6M
Virology CoreP30AI027767 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI OLAF KUTSCH · 1988 to 2026
$84.1M
Virus & Reservoirs CoreP30AI045008 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ROBERT GROSS · 1999 to 2026
$78.6M
STATISTICAL AND DATA MANAGEMENT CENTERU01AI038855 · NIAID · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI HUGHES, MICHAEL DAVID · 1996 to 2006
$78.1M
Studies of Ocular Complications of AIDS - Coordinating CenterU10EY008057 · NEI · JOHNS HOPKINS UNIVERSITY · PI VAN NATTA, MARK L · 1988 to 2012
$78.0M
Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
NATURAL HISTORY OF AIDS IN HOMOSEXUAL MENU01AI035040 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DETELS, ROGER, MARTINEZ-MAZA, OTONIEL · 1993 to 2018
$75.2M
Intramural NIH HHS Z01 CP010176NCATS NIH HHS UL1 TR000083NCATS NIH HHS UL1-TR000083NCI NIH HHS N02 CP055504NCI NIH HHS N02-CP55504NCI NIH HHS R01 CA165937NCI NIH HHS R01-CA165937NCI NIH HHS Z01-CP010176NCI NIH HHS Z01-CP010214NCRR NIH HHS M01 RR000052NCRR NIH HHS MO1-RR-00052NCRR NIH HHS UL1 RR024131NCRR NIH HHS UL1-RR024131NEI NIH HHS K23 EY013707NEI NIH HHS U10 EY008052NEI NIH HHS U10 EY008057NEI NIH HHS U10 EY008067NEI NIH HHS U10-EY08052NEI NIH HHS U10-EY08057NEI NIH HHS U10- EY08067NIAAA NIH HHS R01 AA016893NIAAA NIH HHS R01-AA16893NIAAA NIH HHS U01 AA013566NIAAA NIH HHS U01-AA013566NIAAA NIH HHS U01 AA020790NIAAA NIH HHS U01-AA020790NIAAA NIH HHS U24 AA020794NIAAA NIH HHS U24-AA020794NIAID NIH HHS K01 AI071754NIAID NIH HHS K01-AI071754NIAID NIH HHS K01 AI093197NIAID NIH HHS K01-AI093197NIAID NIH HHS K24 AI065298NIAID NIH HHS K24-AI065298NIAID NIH HHS P30 AI027757NIAID NIH HHS P30 AI027763NIAID NIH HHS P30-AI027763NIAID NIH HHS P30 AI027767NIAID NIH HHS P30 AI036219NIAID NIH HHS P30-AI036219NIAID NIH HHS P30 AI045008NIAID NIH HHS P30 AI050410NIAID NIH HHS P30 AI054999NIAID NIH HHS P30 AI094189NIAID NIH HHS P30-AI094189NIAID NIH HHS P30 AI110527NIAID NIH HHS P30-AI27757NIAID NIH HHS P30-AI27767NIAID NIH HHS P30-AI50410NIAID NIH HHS P30-AI54999NIAID NIH HHS R24 AI067039NIAID NIH HHS R24-AI067039NIAID NIH HHS R56 AI102622NIAID NIH HHS R56-AI102622NIAID NIH HHS U01 AI031834NIAID NIH HHS U01 AI034989NIAID NIH HHS U01 AI034993NIAID NIH HHS U01 AI034994NIAID NIH HHS U01 AI035004NIAID NIH HHS U01 AI035039NIAID NIH HHS U01 AI035040NIAID NIH HHS U01 AI035041NIAID NIH HHS U01 AI035042NIAID NIH HHS U01 AI035043NIAID NIH HHS U01 AI037613NIAID NIH HHS U01 AI037984NIAID NIH HHS U01 AI038855NIAID NIH HHS U01 AI038858NIAID NIH HHS U01 AI042590NIAID NIH HHS U01 AI068634NIAID NIH HHS U01 AI068636NIAID NIH HHS U01 AI069432NIAID NIH HHS U01 AI069434NIAID NIH HHS U01 AI069918NIAID NIH HHS U01-AI069918NIAID NIH HHS U01-AI31834NIAID NIH HHS U01-AI34989NIAID NIH HHS U01-AI34993NIAID NIH HHS U01-AI34994NIAID NIH HHS U01-AI35004NIAID NIH HHS U01-AI35039NIAID NIH HHS U01-AI35040NIAID NIH HHS U01-AI35041NIAID NIH HHS U01-AI35042NIAID NIH HHS U01-AI35043NIAID NIH HHS U01-AI37613NIAID NIH HHS U01-AI37984NIAID NIH HHS U01-AI38855NIAID NIH HHS U01-AI38858NIAID NIH HHS U01-AI42590NIAID NIH HHS U01-AI68634NIAID NIH HHS U01-AI68636NIAID NIH HHS U01-AI69432NIAID NIH HHS U01-AI69434NICHD NIH HHS U01 HD032632NICHD NIH HHS U01-HD32632NIDA NIH HHS F31 DA035713NIDA NIH HHS F31-DA035713NIDA NIH HHS R01 DA004334NIDA NIH HHS R01 DA011602NIDA NIH HHS R01 DA012568NIDA NIH HHS R01-DA04334NIDA NIH HHS R01-DA11602NIDA NIH HHS R01-DA12568NIDA NIH HHS U01-DA0356935NIMHD NIH HHS G12 MD007583NIMHD NIH HHS G12- MD007583NIMHD NIH HHS U54 MD007587NIMHD NIH HHS U54- MD007587NIMH NIH HHS P30 MH062246NIMH NIH HHS P30-MH62246PHS HHS K24-00432
6 · The paper itself

Abstract

objectiveTo understand geographic variations in clinical retention, a central component of the HIV care continuum and key to improving individual- and population-level HIV outcomes.

designWe evaluated retention by US region in a retrospective observational study.

methodsAdults receiving care from 2000-2010 in 12 clinical cohorts of the North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD) contributed data. Individuals were assigned to Centers for Disease Control and Prevention (CDC)-defined regions by residential data (10 cohorts) and clinic location as proxy (2 cohorts). Retention was ≥2 primary HIV outpatient visits within a calendar year, >90 days apart. Trends and regional differences were analyzed using modified Poisson regression with clustering, adjusting for time in care, age, sex, race/ethnicity, and HIV risk, and stratified by baseline CD4+ count.

resultsAmong 78,993 adults with 444,212 person-years of follow-up, median time in care was 7 years (Interquartile Range: 4-9). Retention increased from 2000 to 2010: from 73% (5,000/6,875) to 85% (7,189/8,462) in the Northeast, 75% (1,778/2,356) to 87% (1,630/1,880) in the Midwest, 68% (8,451/12,417) to 80% (9,892/12,304) in the South, and 68% (5,147/7,520) to 72% (6,401/8,895) in the West. In adjusted analyses, retention improved over time in all regions (p<0.01, trend), although the average percent retained lagged in the West and South vs. the Northeast (p<0.01).

conclusionsIn our population, retention improved, though regional differences persisted even after adjusting for demographic and HIV risk factors. These data demonstrate regional differences in the US which may affect patient care, despite national care recommendations.

Indexed as

GeographyPatient CareAdultConfidence IntervalsDemographyHIV InfectionsHumansMiddle AgedOdds RatioTime FactorsUnited States

Identifiers

PMID26752637
PMCPMC4708981

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.