ArticlePloS one2016
Disposable Soma Theory and the Evolution of Maternal Effects on Ageing.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- SIRT6 overexpression counteracts chromatin aging in the male murine liver.Nature communications · 2026Article
- Familial investigation of two cases of pseudohypoparathyroidism.Frontiers in endocrinology · 2026Article
- Consistent and flexible maternal effects: how the environments of a mother influence the offspring phenotype.Biological reviews of the Cambridge Philosophical Society · 2025Review
- Article
- Mating reconciles fitness and fecundity by switching diet preference in flies.Nature communications · 2024Article
- Older mothers produce more successful daughters.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Skeletal muscle as an experimental model of choice to study tissue aging and rejuvenation.Skeletal muscle · 2020Review
- Female Fertility Has a Negative Relationship With Longevity in Chinese Oldest-Old Population: A Cross-Sectional Study.Frontiers in endocrinology · 2020Article
- Intergenerational effects on offspring telomere length: interactions among maternal age, stress exposure and offspring sex.Proceedings. Biological sciences · 2019Article
- Maternal age alters offspring lifespan, fitness, and lifespan extension under caloric restriction.Scientific reports · 2019Article
- A Tale of Two Concepts: Harmonizing the Free Radical and Antagonistic Pleiotropy Theories of Aging.Antioxidants & redox signaling · 2018Review
- Sexual competition and the evolution of condition-dependent ageing.Evolution letters · 2018Article
- Environmental conditions shape the temporal pattern of investment in reproduction and survival.Proceedings. Biological sciences · 2018Article
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Authors and funding
3 authors.
Funding
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Abstract
Maternal effects are ubiquitous in nature and affect a wide range of offspring phenotypes. Recent research suggests that maternal effects also contribute to ageing, but the theoretical basis for these observations is poorly understood. Here we develop a simple model to derive expectations for (i) if maternal effects on ageing evolve; (ii) the strength of maternal effects on ageing relative to direct environmental effects; and (iii) the predicted relationships between environmental quality, maternal age and offspring lifespan. Our model is based on the disposable soma theory of ageing, and the key assumption is thus that mothers trade off their own somatic maintenance against investment in offspring. This trade-off affects the biological age of offspring at birth in terms of accumulated damage, as indicated by biomarkers such as oxidative stress or telomere length. We find that the optimal allocation between investment in maternal somatic investment and investment in offspring results in old mothers and mothers with low resource availability producing offspring with reduced life span. Furthermore, the effects are interactive, such that the strongest maternal age effects on offspring lifespan are found under low resource availability. These findings are broadly consistent with results from laboratory studies investigating the onset and rate of ageing and field studies examining maternal effects on ageing in the wild.
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