Evidence map›Paper›PMID 26752122›Full record

ArticleNeuropsychology2016

Cognitive, emotion control, and motor performance of adolescents in the NCANDA study: Contributions from alcohol consumption, age, sex, ethnicity, and family history of addiction.

Edith V Sullivan, Ty Brumback, Susan F Tapert, Rosemary Fama, Devin Prouty, Sandra A Brown, Kevin Cummins, Wesley K Thompson, Ian M Colrain, Fiona C Baker and 10 more

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Neuropsychology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 46 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 2 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 2 syntheses or guidelines pooled it, 71 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Adolescent alcohol use is linked to disruptions in age-appropriate cortical thinning: an unsupervised machine learning approach.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors at 7 institutions in 3 countries.

Edith V SullivanDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine.
Ty BrumbackDepartment of Psychiatry, University of California, San Diego.
Susan F TapertPsychology Service, Veterans Affairs San Diego Healthcare System.
Rosemary FamaDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine.
Devin Prouty
Sandra A BrownDepartment of Psychiatry, University of California, San Diego.
Kevin CumminsDepartment of Psychiatry, University of California, San Diego.
Wesley K ThompsonDepartment of Psychiatry, University of California, San Diego.
Ian M Colrain
Fiona C Baker
Michael D De BellisHealthy Childhood Brain Development Research Program, Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine.
Stephen R HooperDepartment of Allied Health Sciences, University of North Carolina School of Medicine.
Duncan B ClarkDepartment of Psychiatry, University of Pittsburgh.
Tammy ChungDepartment of Psychiatry, University of Pittsburgh.
Bonnie J NagelDepartments of Psychiatry and Behavioral Neuroscience, Oregon Health and Sciences University.
B Nolan NicholsDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine.
Torsten Rohlfing
Weiwei Chu
Kilian M PohlDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine.
Adolf PfefferbaumDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine.
Stanford University · USUniversity of California San Diego · USUniversity of Pittsburgh · USHealth and Human Development (2HD) Research Network · CMOregon Health & Science University · USUniversity of Health and Allied Sciences · GHVA San Diego Healthcare System · US

Funding

Sex Differences in Autonomic Nervous System Function and Depression Across AdolescenceU01AA021696 · NIAAA · SRI INTERNATIONAL · PI Fiona C Baker · 2012 to 2026
$12.2M
NCANDA: Data Analysis Resource - Uploading Legacy Data to NDAU24AA021697 · NIAAA · STANFORD UNIVERSITY · PI Adolf Pfefferbaum, Kilian Maria Pohl · 2016 to 2026
$12.2M
National Consortium on Alcohol and NeuroDevelopment in Adolescence: San DiegoU01AA021692 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Susan F. Tapert · 2012 to 2026
$11.8M
NCANDA Research Project Site: DukeU01AA021681 · NIAAA · DUKE UNIVERSITY · PI DAVID B. GOLDSTON · 2012 to 2026
$9.8M
The TEEN Study: The Impact of Adolescent Drinking on Connectivity in the BrainU01AA021691 · NIAAA · OREGON HEALTH & SCIENCE UNIVERSITY · PI Angelica Marie Morales, Bonnie J. Nagel · 2012 to 2026
$8.5M
NCANDA Research Project Site: University of Pittsburgh (NCANDA-PITT)U01AA021690 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DUNCAN B. CLARK, BEATRIZ LUNA · 2012 to 2026
$7.6M
National Consortium on Alcohol and NeuroDevelopment in Adolescence (NCANDA): Administrative ResourceU24AA021695 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SANDRA A BROWN, Susan F. Tapert · 2016 to 2026
$6.0M
N-CANDA: DATA ANALYSIS COMPONENTU01AA021697 · NIAAA · SRI INTERNATIONAL · PI PFEFFERBAUM, ADOLF, POHL, KILIAN MARIA · 2012 to 2015
$3.6M
Translational Studies of Brain Circuitry Disrupted by AlcoholismK05AA017168 · NIAAA · STANFORD UNIVERSITY · PI SULLIVAN, EDITH VIONI · 2008 to 2017
$2.2M
National Consortium on Alcohol and NeuroDevelopment in Adolescence: AdminU01AA021695 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BROWN, SANDRA A, TAPERT, SUSAN F · 2012 to 2015
$2.1M
NIAAA NIH HHS K05 AA017168NIAAA NIH HHS U01 AA021681NIAAA NIH HHS U01 AA021690NIAAA NIH HHS U01 AA021691NIAAA NIH HHS U01 AA021692NIAAA NIH HHS U01 AA021695NIAAA NIH HHS U01 AA021696NIAAA NIH HHS U01 AA021697NIAAA NIH HHS U24 AA021695NIAAA NIH HHS U24 AA021697
6 · The paper itself

Abstract

objectiveTo investigate development of cognitive and motor functions in healthy adolescents and to explore whether hazardous drinking affects the normal developmental course of those functions.

methodParticipants were 831 adolescents recruited across 5 United States sites of the National Consortium on Alcohol and NeuroDevelopment in Adolescence 692 met criteria for no/low alcohol exposure, and 139 exceeded drinking thresholds. Cross-sectional, baseline data were collected with computerized and traditional neuropsychological tests assessing 8 functional domains expressed as composite scores. General additive modeling evaluated factors potentially modulating performance (age, sex, ethnicity, socioeconomic status, and pubertal developmental stage).

resultsOlder no/low-drinking participants achieved better scores than younger ones on 5 accuracy composites (general ability, abstraction, attention, emotion, and balance). Speeded responses for attention, motor speed, and general ability were sensitive to age and pubertal development. The exceeds-threshold group (accounting for age, sex, and other demographic factors) performed significantly below the no/low-drinking group on balance accuracy and on general ability, attention, episodic memory, emotion, and motor speed scores and showed evidence for faster speed at the expense of accuracy. Delay Discounting performance was consistent with poor impulse control in the younger no/low drinkers and in exceeds-threshold drinkers regardless of age.

conclusionsHigher achievement with older age and pubertal stage in general ability, abstraction, attention, emotion, and balance suggests continued functional development through adolescence, possibly supported by concurrently maturing frontal, limbic, and cerebellar brain systems. Determination of whether low scores by the exceeds-threshold group resulted from drinking or from other preexisting factors requires longitudinal study. (PsycINFO Database Record

Indexed as

Underage DrinkingAdolescentAdolescent DevelopmentAlcohol DrinkingCognitionCross-Sectional StudiesEmotionsExecutive FunctionFemaleHumansMalePsychomotor PerformanceUnited States

Identifiers

PMID26752122
PMCPMC4840074
OpenAlexW2238017706

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.