Evidence map›Paper›PMID 26751491›Full record

ReviewBiomolecules2016

Guardian of Genetic Messenger-RNA-Binding Proteins.

Antje Anji, Meena Kumari

Open access · goldAbstract readReview
In one paragraph

Review in Biomolecules, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Antje AnjiDepartment of Anatomy and Physiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506, USA. aanji@vet.ksu.edu.
Meena KumariDepartment of Anatomy and Physiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506, USA. mkumari@vet.ksu.edu.
Kansas State University · US

Funding

ETHANOL INDUCED NMDA R1 MRNA STABILIZATIONR01AA012070 · NIAAA · UNIVERSITY OF TEXAS HLTH SCI CTR SAN ANT · PI KUMARI, MEENA · 1999 to 2013
$1.8M
NIAAA NIH HHS AA12070NIAAA NIH HHS R01 AA012070
6 · The paper itself

Abstract

RNA in cells is always associated with RNA-binding proteins that regulate all aspects of RNA metabolism including RNA splicing, export from the nucleus, RNA localization, mRNA turn-over as well as translation. Given their diverse functions, cells express a variety of RNA-binding proteins, which play important roles in the pathologies of a number of diseases. In this review we focus on the effect of alcohol on different RNA-binding proteins and their possible contribution to alcohol-related disorders, and discuss the role of these proteins in the development of neurological diseases and cancer. We further discuss the conventional methods and newer techniques that are employed to identify RNA-binding proteins.

Indexed as

Alcohol-Related DisordersAlcoholsBinding SitesGene Expression RegulationHumansNeoplasmsNervous System DiseasesRNA-Binding ProteinsRNA, MessengerRNA SplicingRNA StabilityAlcoholsRNA-Binding ProteinsRNA, Messengeralcoholcancergene expressionmRNA splicingmRNA stabilityneurological diseasesRNA-binding proteins

Identifiers

PMID26751491
PMCPMC4808798
OpenAlexW2225370160

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.