Evidence map›Paper›PMID 26751378›Full record

ArticlePloS one2016

Neurokernel: An Open Source Platform for Emulating the Fruit Fly Brain.

Lev E Givon, Aurel A Lazar

Abstract read
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Generating Executable Models of the Drosophila Central Complex.Frontiers in behavioral neuroscience · 2017
    Article
  11. Toward Whole-Body Connectomics.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Lev E GivonDepartment of Electrical Engineering, Columbia University, New York, NY 10027, United States of America.
Aurel A LazarDepartment of Electrical Engineering, Columbia University, New York, NY 10027, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have developed an open software platform called Neurokernel for collaborative development of comprehensive models of the brain of the fruit fly Drosophila melanogaster and their execution and testing on multiple Graphics Processing Units (GPUs). Neurokernel provides a programming model that capitalizes upon the structural organization of the fly brain into a fixed number of functional modules to distinguish between these modules' local information processing capabilities and the connectivity patterns that link them. By defining mandatory communication interfaces that specify how data is transmitted between models of each of these modules regardless of their internal design, Neurokernel explicitly enables multiple researchers to collaboratively model the fruit fly's entire brain by integration of their independently developed models of its constituent processing units. We demonstrate the power of Neurokernel's model integration by combining independently developed models of the retina and lamina neuropils in the fly's visual system and by demonstrating their neuroinformation processing capability. We also illustrate Neurokernel's ability to take advantage of direct GPU-to-GPU data transfers with benchmarks that demonstrate scaling of Neurokernel's communication performance both over the number of interface ports exposed by an emulation's constituent modules and the total number of modules comprised by an emulation.

Indexed as

SoftwareAlgorithmsAnimalsBrainBrain MappingComputational BiologyComputer GraphicsComputer SimulationDrosophila melanogasterNeuronsProgramming LanguagesRetina

Identifiers

PMID26751378
PMCPMC4709234

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.