ArticlePloS one2016
Patient Characteristics and Comorbidities Influence Walking Distances in Symptomatic Peripheral Arterial Disease: A Large One-Year Physiotherapy Cohort Study.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Living a burdensome and demanding life: A qualitative systematic review of the patients experiences of peripheral arterial disease.PloS one · 2018Pooled it
- Pooled it
- Exercise in claudicants increase or decrease walking ability and the response relates to mitochondrial function.Journal of translational medicine · 2017Trial
- Sex differences in outcomes of exercise therapy for patients with intermittent claudication: A scoping review.Seminars in vascular surgery · 2023Article
- Foot Temperature by Infrared Thermography in Patients with Peripheral Artery Disease before and after Structured Home-Based Exercise: A Gender-Based Observational Study.Journal of personalized medicine · 2023Article
- Lower All-Cause Mortality Risk in Females and Males with Peripheral Artery Disease following Pain-Free Home-Based Exercise: A 7-Year Observational Study.Journal of personalized medicine · 2023Article
- A Fitness-Fatigue Model of Performance in Peripheral Artery Disease: Predicted and Measured Effects of a Pain-Free Exercise Program.Journal of personalized medicine · 2022Article
- Sex Differences in Peripheral Artery Disease.Circulation research · 2022Review
- Metabolite patterns associated with individual response to supervised exercise therapy in patients with intermittent claudication.JVS-vascular science · 2022Article
- Beneficial Effects of Robot-Assisted Gait Training on Functional Recovery in Women after Stroke: A Cohort Study.Medicina (Kaunas, Lithuania) · 2021Article
- Individual Differences in Response to Supervised Exercise Therapy for Peripheral Artery Disease.Western journal of nursing research · 2021Article
- Gender Differences in Outcomes Following a Pain-Free, Home-Based Exercise Program for Claudication.Journal of women's health (2002) · 2019Article
- Experience Implementing Supervised Exercise Therapy for Peripheral Artery Disease.Journal of clinical exercise physiology · 2019Article
- Article
- Predictors of Improved Walking after a Supervised Walking Exercise Program in Men and Women with Peripheral Artery Disease.International journal of vascular medicine · 2016Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of this study is to investigate the association between age, gender, body-mass index, smoking behavior, orthopedic comorbidity, neurologic comorbidity, cardiac comorbidity, vascular comorbidity, pulmonic comorbidity, internal comorbidity and Initial Claudication Distance during and after Supervised Exercise Therapy at 1, 3, 6 and 12 months in a large sample of patients with Intermittent Claudication.
methodsData was prospectively collected in standard physiotherapy care. Patients received Supervised Exercise Therapy according to the guideline Intermittent Claudication of the Royal Dutch Society for Physiotherapy. Three-level mixed linear regression analysis was carried out to analyze the association between patient characteristics, comorbidities and Initial Claudication Distance at 1, 3, 6 and 12 months.
resultsData from 2995 patients was analyzed. Results showed that being female, advanced age and a high body-mass index were associated with lower Initial Claudication Distance at all-time points (p = 0.000). Besides, a negative association between cardiac comorbidity and Initial Claudication Distance was revealed (p = 0.011). The interaction time by age, time by body-mass index and time by vascular comorbidity were significantly associated with Initial Claudication Distance (p≤ 0.05). Per year increase in age (range: 33-93 years), the reduction in Initial Claudication Distance was 8m after 12 months of Supervised Exercise Therapy. One unit increase in body-mass index (range: 16-44 kg/m2) led to 10 m less improvement in Initial Claudication Distance after 12 months and for vascular comorbidity the reduction in improvement was 85 m after 12 months.
conclusionsThis study reveals that females, patients at advanced age, patients with a high body-mass index and cardiac comorbidity are more likely to show less improvement in Initial Claudication Distances (ICD) after 1, 3, 6 and 12 months of Supervised Exercise Therapy. Further research should elucidate treatment adaptations that optimize treatment outcomes for these subgroups.
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