Evidence map›Paper›PMID 26750123›Full record

ReviewCurrent microbiology2016

Carotenoid Production by Halophilic Archaea Under Different Culture Conditions.

Rossana Calegari-Santos, Ricardo Alexandre Diogo, José Domingos Fontana, Tania Maria Bordin Bonfim

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 88 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Microbial conversion of biodiesel waste for carotenoid production.Frontiers in bioengineering and biotechnology · 2026
    Article
  5. Bacterioruberin (CNutrients · 2025
    Review
  6. Microbial Bacterioruberin: A Comprehensive Review.Indian journal of microbiology · 2024
    Review
  7. Halocins and CMarine drugs · 2024
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Enhanced Production of CJournal of microbiology and biotechnology · 2022
    Article
  20. CFolia microbiologica · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Rossana Calegari-SantosDepartment of Pharmacy, Enzymology and Fermentation Technology Laboratory, Federal University of Paraná, Av. Pref. Lothário Meissner, 632, Curitiba, Paraná, 80210-170, Brazil.
Ricardo Alexandre DiogoPolytechnic School, Control and Automation Engineering, Pontifical Catholic University of Paraná, Rua Imaculada Conceição, 1155, Curitiba, Paraná, 80215-901, Brazil.
José Domingos FontanaDepartment of Chemistry and Biology, Federal Technological University of Paraná, Rua Deputado Heitor Alencar Furtado, 5000, Curitiba, Paraná, 81280-340, Brazil.
Tania Maria Bordin BonfimDepartment of Pharmacy, Enzymology and Fermentation Technology Laboratory, Federal University of Paraná, Av. Pref. Lothário Meissner, 632, Curitiba, Paraná, 80210-170, Brazil. tbonfim@ufpr.br.
Universidade Federal do Paraná · BRPontifícia Universidade Católica do Paraná · BRUniversidade Tecnológica Federal do Paraná · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carotenoids are pigments that may be used as colorants and antioxidants in food, pharmaceutical, and cosmetic industries. Since they also benefit human health, great efforts have been undertaken to search for natural sources of carotenoids, including microbial ones. The optimization of culture conditions to increase carotenoid yield is one of the strategies used to minimize the high cost of carotenoid production by microorganisms. Halophilic archaea are capable of producing carotenoids according to culture conditions. Their main carotenoid is bacterioruberin with 50 carbon atoms. In fact, the carotenoid has important biological functions since it acts as cell membrane reinforcement and it protects the microorganism against DNA damaging agents. Moreover, carotenoid extracts from halophilic archaea have shown high antioxidant capacity. Therefore, current review summarizes the effect of different culture conditions such as salt and carbon source concentrations in the medium, light incidence, and oxygen tension on carotenoid production by halophilic archaea and the strategies such as optimization methodology and two-stage cultivation already used to increase the carotenoid yield of these microorganisms.

Indexed as

ArchaeaCarotenoidsCulture MediaSodium ChlorideCarotenoidsCulture MediaSodium Chloride

Identifiers

PMID26750123
OpenAlexW2237477864

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.