ArticleAddiction (Abingdon, England)2016
Polysomnographic measures of sleep in cocaine dependence and alcohol dependence: Implications for age-related loss of slow wave, stage 3 sleep.
Article in Addiction (Abingdon, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Objective and subjective measurement of sleep in people who use substances: Emerging evidence and recommendations from a systematic review.Journal of sleep research · 2025Pooled it
- Longitudinal changes in sleep quality in male patients with alcohol dependence receiving far-infrared ray therapy: associations with alterations in circulating pro-inflammatory cytokines.BMC psychiatry · 2025Trial
- Sleep alterations in substance use disorders: a systematic review and meta-analysis.EClinicalMedicine · 2026Article
- Validity and Reliability of the Korean Version of Substance Use Sleep Scale for Patients With Alcohol Use Disorder.Psychiatry investigation · 2025Article
- Sleep and psychiatric disorders: Bidirectional interactions and shared neurobiological mechanisms.PLOS mental health · 2025Review
- Analysis of the determinants of sleep quality in a Spanish population: a study protocol for a cross-sectional study.BMJ open · 2023Observational
- Effect of short-term mindfulness-based stress reduction on sleep quality in male patients with alcohol use disorder.Frontiers in psychiatry · 2023Article
- Ageing and older people who use illicit opioids, cocaine or methamphetamine: a scoping review and literature map.Addiction (Abingdon, England) · 2022Article
- Associations between common sleep disturbances and cardiovascular risk in patients with obstructive sleep apnea: A large-scale cross-sectional study.Frontiers in cardiovascular medicine · 2022Article
- Sleep and alcohol use among young adult drinkers with Insomnia: A daily process model.Addictive behaviors · 2021Article
- Interaction between cocaine use and sleep behavior: A comprehensive review of cocaine's disrupting influence on sleep behavior and sleep disruptions influence on reward seeking.Pharmacology, biochemistry, and behavior · 2021Review
- Enhancement of cue-induced reinstatement of alcohol seeking by acute total sleep restriction in male Wistar rats.Pharmacology, biochemistry, and behavior · 2021Article
- The effect of alcohol withdrawal syndrome severity on sleep, brain and cognition.Brain communications · 2020Article
- The Rostromedial Tegmental Nucleus: Anatomical Studies and Roles in Sleep and Substance Addictions in Rats and Mice.Nature and science of sleep · 2020Review
- Alcohol use disorder and sleep disturbances: a feed-forward allostatic framework.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2020Review
- Sleep Disorder in Drug Addiction: Treatment With Transcranial Magnetic Stimulation.Frontiers in psychiatry · 2019Article
- Differential Effects of Addictive Drugs on Sleep and Sleep Stages.Journal of addiction research (OPAST Group) · 2019Article
- Sleep deprivation alters the time course but not magnitude of locomotor sensitization to cocaine.Scientific reports · 2018Article
- Dose response of acute cocaine on sleep/waking behavior in mice.Neurobiology of sleep and circadian rhythms · 2018Article
- The rostromedial tegmental nucleus is essential for non-rapid eye movement sleep.PLoS biology · 2018Article
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Funding
Abstract
BACKGROUND AND
aimsSleep disturbance is a prominent complaint in cocaine and alcohol dependence. This controlled study evaluated differences of polysomnographic (PSG) sleep in cocaine- and alcohol-dependent subjects, and examined whether substance dependence interacts with age to alter slow wave sleep and rapid eye movement (REM) sleep.
designCross-sectional comparison.
settingLos Angeles and San Diego, CA, USA.
participantsAbstinent cocaine-dependent subjects (n = 32), abstinent alcohol-dependent subjects (n = 73) and controls (n = 108); mean age 40.3 years recruited 2005-12. MEASUREMENTS: PSG measures of sleep continuity and sleep architecture primary outcomes of Stage 3 sleep and REM sleep. Covariates included age, ethnicity, education, smoking, body mass index and depressive symptoms.
findingsCompared with controls, both groups of substance dependent subjects showed loss of Stage 3 sleep (P < 0.001). A substance dependence × age interaction was found in which both cocaine- and alcohol-dependent groups showed loss of Stage 3 sleep at an earlier age than controls (P < 0.05 for all), and cocaine-dependent subjects showed loss of Stage 3 sleep at an earlier age than alcoholics (P < 0.05). Compared with controls, REM sleep was increased in both substance-dependent groups (P < 0.001), and cocaine and alcohol dependence were associated with earlier age-related increase in REM sleep (P < 0.05 for all).
conclusionsCocaine and alcohol dependence appear to be associated with marked disturbances of sleep architecture, including increased rapid eye movement sleep and accelerated age-related loss of slow wave, Stage 3 sleep.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.