ArticleProceedings of the National Academy of Sciences of the United States of America1989
Evidence for two pathways of meiotic intrachromosomal recombination in yeast.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1989. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 38 citations in OpenAlex.
- Inhibition of homologous recombination by a cohesin-associated clamp complex recruited to the rDNA recombination enhancer.Genes & development · 2006Article
- Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair.Microbiology and molecular biology reviews : MMBR · 2002Review
- Genetic requirements for spontaneous and transcription-stimulated mitotic recombination in Saccharomyces cerevisiae.Genetics · 2002Article
- Homologous recombination in planta is stimulated in the absence of Rad50.EMBO reports · 2001Article
- Rare germinal unequal crossing-over leading to recombinant gene formation and gene duplication in Arabidopsis thaliana.Proceedings of the National Academy of Sciences of the United States of America · 1999Article
- Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae.Microbiology and molecular biology reviews : MMBR · 1999Review
- Regulation of Cdc28 cyclin-dependent protein kinase activity during the cell cycle of the yeast Saccharomyces cerevisiae.Microbiology and molecular biology reviews : MMBR · 1998Review
- Direct evidence for SIR2 modulation of chromatin structure in yeast rDNA.The EMBO journal · 1997Article
- Mutations in the yeast SRB2 general transcription factor suppress hpr1-induced recombination and show defects in DNA repair.Genetics · 1996Article
- Chromosome dynamics in rad12 mutants of Coprinus cinereus.Chromosoma · 1995Article
- The yeast MER2 gene is required for chromosome synapsis and the initiation of meiotic recombination.Genetics · 1995Article
- RAD58 (XRS4)--a new gene in the RAD52 epistasis group.Current genetics · 1995Article
- Bdf1, a yeast chromosomal protein required for sporulation.Molecular and cellular biology · 1995Article
- SPO13 negatively regulates the progression of mitotic and meiotic nuclear division in Saccharomyces cerevisiae.Genetics · 1994Article
- Effect of mutations in genes affecting homologous recombination on restriction enzyme-mediated and illegitimate recombination in Saccharomyces cerevisiae.Molecular and cellular biology · 1994Article
- Unrepaired heteroduplex DNA in Saccharomyces cerevisiae is decreased in RAD1 RAD52-independent recombination.Genetics · 1994Article
- Mutations in XRS2 and RAD50 delay but do not prevent mating-type switching in Saccharomyces cerevisiae.Molecular and cellular biology · 1994Article
- Expression of the Saccharomyces cerevisiae RAD50 gene during meiosis: steady-state transcript levels rise and fall while steady-state protein levels remain constant.Molecular & general genetics : MGG · 1993Article
- Replication-dependent sister chromatid recombination in rad1 mutants of Saccharomyces cerevisiae.Genetics · 1993Article
- XRS2, a DNA repair gene of Saccharomyces cerevisiae, is needed for meiotic recombination.Genetics · 1992Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
This study shows that RAD50, a yeast DNA repair gene required for meiotic interchromosomal exchange between homologs, also is required for meiotic intrachromosomal recombination. However, only intrachromosomal events in nonribosomal DNA are dependent on RAD50; those in ribosomal DNA (rRNA-encoding DNA) occur in the absence of this gene. Furthermore, nonribosomal DNA sequences retain their RAD50-dependence even when inserted into the ribosomal DNA array. We argue that these data provide evidence for at least two pathways of meiotic intrachromosomal recombination whose activity depends on the specific sequences involved or their structural context in the chromosome. In contrast to its role in meiosis, RAD50 is not required for either inter- or intrachromosomal spontaneous mitotic recombination.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.