ArticleJournal of the science of food and agriculture2016
In vitro and in vivo evaluation of the prebiotic effect of raw and roasted almonds (Prunus amygdalus).
Article in Journal of the science of food and agriculture, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Effects of Nut Intake on Gut Microbiome Composition and Gut Function in Adults: A Systematic Review and Meta-analysis.Advances in nutrition (Bethesda, Md.) · 2025Pooled it
- Pooled it
- The impact of almonds and almond processing on gastrointestinal physiology, luminal microbiology, and gastrointestinal symptoms: a randomized controlled trial and mastication study.The American journal of clinical nutrition · 2022Trial
- A Walnut-Enriched Diet Affects Gut Microbiome in Healthy Caucasian Subjects: A Randomized, Controlled Trial.Nutrients · 2018Trial
- An Overview of Targeting Some Cancer Hallmarks with Plant Polyphenols: A Step Toward Precision.Sub-cellular biochemistry · 2026Review
- Almond By-Products: A Comprehensive Review of Composition, Bioactivities, and Influencing Factors.Foods (Basel, Switzerland) · 2025Review
- The Effects of Almond Consumption on Cardiovascular Health and Gut Microbiome: A Comprehensive Review.Nutrients · 2024Review
- Nutrition at the Intersection between Gut Microbiota Eubiosis and Effective Management of Type 2 Diabetes.Nutrients · 2024Review
- Recent Innovations in Non-dairy Prebiotics and Probiotics: Physiological Potential, Applications, and Characterization.Probiotics and antimicrobial proteins · 2023Review
- An Updated Review on Prebiotics: Insights on Potentials of Food Seeds Waste as Source of Potential Prebiotics.Molecules (Basel, Switzerland) · 2022Review
- Evaluating the Potential of the Defatted By-Product ofFoods (Basel, Switzerland) · 2021Article
- Partial Replacement of Animal Fat with Full-Fat Almond in Broiler Chicken Diets: Performance, Nutrient Digestibility, Blood Profile, Cecal-Fecal Microflora Composition, and Foot-Pad Dermatitis.Animals : an open access journal from MDPI · 2021Article
- Almond By-Products: Valorization for Sustainability and Competitiveness of the Industry.Foods (Basel, Switzerland) · 2021Review
- Volatile Profile of Nuts, Key Odorants and Analytical Methods for Quantification.Foods (Basel, Switzerland) · 2021Review
- Effect of Frying and Roasting Processes on the Oxidative Stability of Sunflower Seeds (Foods (Basel, Switzerland) · 2021Article
- Plant Prebiotics and Their Role in the Amelioration of Diseases.Biomolecules · 2021Review
- Article
- Understanding the Fate of Almond (Nutrients · 2020Article
- Almonds (Nutrients · 2020Review
- Plant-Based Fat, Dietary Patterns Rich in Vegetable Fat and Gut Microbiota Modulation.Frontiers in nutrition · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlmonds contain considerable amounts of potential prebiotic components, and the roasting process may alter these components. The aim of this study was to compare the in vitro fermentation properties and in vivo prebiotic effect of raw and roasted almonds.
resultsIn vitro, predigested raw and roasted almonds promoted the growth of Lactobacillus acidophilus (La-14) and Bifidobacterium breve (JCM 1192), and no significant differences were found between these two nuts. In a 4-week animal trial, daily intake of raw or roasted almonds promoted the population of Bifidobacterium spp. and Lactobacillus spp. and inhibited the growth of Enterococcus spp. in faeces and caecal contains of rats. Compared with roasted almonds, raw almonds had a greater bifidobacteria promotion effect. Besides, significantly higher β-galactosidase activity and lower β-glucuronidase and azoreductase activities in faeces or caecal contents of rats were observed with raw almonds than with roasted almonds. While, in terms of metabolic effects, the ingestion of roasted almonds resulted in significantly greater intestinal lipase activities.
conclusionBoth raw and roasted almonds exhibit potential prebiotic effects, including regulation of intestinal bacteria and improved metabolic activities. The roasting process may slightly reduce the prebiotic effects of almonds but significantly improve the metabolic effects
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.