Evidence map›Paper›PMID 26749145›Full record

Observational studyJournal of artificial organs : the official journal of the Japanese Society for Artificial Organs2016

Heart valve surgery in hemodialysis-dependent patients: nutrition status impact on surgical outcome.

Koji Kawahito, Kei Aizawa, Shinichi Oki, Tsutomu Saito, Yoshio Misawa

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Risk analysis using the prognostic nutritional index in hemodialysis-dependent patients undergoing cardiac surgery.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2018
    Observational
  3. Journal of Artificial Organs 2016: the year in review : Journal of Artificial Organs Editorial Committee.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2017
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Koji KawahitoDepartment of Cardiovascular Surgery, Jichi Medical School, Yakushiji 3311-1, Shimotsuke, Tochigi, 329-0498, Japan. kj_kawahito@msn.com.
Kei AizawaDepartment of Cardiovascular Surgery, Jichi Medical School, Yakushiji 3311-1, Shimotsuke, Tochigi, 329-0498, Japan.
Shinichi OkiDepartment of Cardiovascular Surgery, Jichi Medical School, Yakushiji 3311-1, Shimotsuke, Tochigi, 329-0498, Japan.
Tsutomu SaitoDepartment of Cardiovascular Surgery, Jichi Medical School, Yakushiji 3311-1, Shimotsuke, Tochigi, 329-0498, Japan.
Yoshio MisawaDepartment of Cardiovascular Surgery, Jichi Medical School, Yakushiji 3311-1, Shimotsuke, Tochigi, 329-0498, Japan.
Jichi Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Valve surgery in hemodialysis-dependent patients is associated with postoperative complications and a high mortality rate, and such patients frequently suffer cachexia. This study aimed to determine pre- and intraoperative risk factors associated with in-hospital mortality and long-term survival in hemodialysis-dependent patients undergoing heart valve surgery from the viewpoint of nutrition status. Eighty-seven hemodialysis-dependent patients who underwent valve surgery between January 1998 and October 2015 were retrospectively reviewed. Thirty-seven potential perioperative risk factors were evaluated. The in-hospital mortality rate was 12.6 % (11 patients). Univariate analysis identified New York Heart Association Functional Classification III or IV, emaciation (body mass index <17.6 kg/m(2)), total cholesterol <120 mg/dl, serum albumin <3.0 mg/dl, emergent/urgent surgery, and intraoperative blood transfusion >3000 ml as predictors of in-hospital death. Multivariate logistic regression analysis confirmed low serum albumin <3.0 mg/dl (hazard ratio 7.22; p = 0.032) and emergent/urgent operation (hazard ratio 43.57; p = 0.035) as independent predictors of in-hospital death. The 1- and 3-year actuarial survival rates were 64.9 ± 5.4 and 51.8 ± 5.8 %, respectively. Long-term survival estimated by log-rank test was negatively impacted by anemia (hemoglobin <10 mg/dl), low serum albumin, emergent/urgent operation, and infective endocarditis. Multivariate analysis using Cox proportional hazards modeling indicated low serum albumin (hazard ratio 2.12; p = 0.047) and emergent/urgent operation (hazard ratio 8.97; p = 0.0002) as independent predictors of remote death. Hypoalbuminemia and emergent/urgent operation are strong predictors of in-hospital and remote death. Malnutrition before surgery should be considered for operative risk estimation, and adequate preoperative nutrition management may improve surgical outcomes for hemodialysis-dependent patients.

Indexed as

Nutritional StatusRenal DialysisAdultAgedAged, 80 and overCardiac Surgical ProceduresEndocarditis, BacterialFemaleHeart Valve Prosthesis ImplantationHeart ValvesHospital MortalityHumansJapanKidney Failure, ChronicMaleMiddle AgedHeart valve replacementKidneyNutritionRenal function failure

Identifiers

PMID26749145
OpenAlexW2233114576

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.