Evidence map›Paper›PMID 26749026›Full record

Trial reportAnaesthesia2016

A randomised controlled trial of peri-operative lidocaine infusions for open radical prostatectomy.

L Weinberg, C Rachbuch, S Ting, W Howard, M Yeomans, I Gordon, L McNicol, K James, D Story, C Christophi

Erratum issuedOpen access · bronzeAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Anaesthesia, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Observational
  5. Review
  6. Article
  7. Review
  8. Article
  9. Correction.Anaesthesia · 2016
    Article
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

L WeinbergAnaesthesia, Peri-operative and Pain Medicine, University of Melbourne, Melbourne, Victoria, Australia.
C RachbuchDepartment of Anaesthesia, Eastern Health, Box Hill, Victoria, Australia.
S TingDepartment of Anaesthesia, Monash Health, Clayton, Victoria, Australia.
W HowardAcute Pain Service, Austin Hospital, Heidelberg, Victoria, Australia.
M YeomansAcute Pain Service, Austin Hospital, Heidelberg, Victoria, Australia.
I GordonSchool of Mathematics and Statistics, University of Melbourne, Melbourne, Victoria, Australia.
L McNicolDepartment of Surgery, University of Melbourne, Melbourne, Victoria, Australia.
K JamesDepartment of Anaesthesia, Austin Hospital, Heidelberg, Victoria, Australia.
D StoryAnaesthesia, Peri-operative and Pain Medicine, University of Melbourne, Melbourne, Victoria, Australia.
C ChristophiDepartment of Surgery, University of Melbourne, Melbourne, Victoria, Australia.
University of Melbourne · AUAustin Hospital · AUEastern Health · AUMarymount University · USMonash Health · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We allocated 76 men scheduled for radical retropubic prostatectomy to peri-operative lidocaine 2% or saline 0.9%: a pre-operative 0.075 ml.kg(-1) intravenous bolus; an intra-operative intravenous infusion at 0.075 ml.kg(-1) .h(-1) ; and 24 hours' postoperative subcutaneous infusion at 0.075 ml.kg(-1) .h(-1) . Lidocaine reduced the postoperative hospital stay by a mean (95% CI) of 1.3 (0.3-2.4) days, p = 0.017, from a mean (SD) of 4.6 (3.2) days with saline. There were no significant differences in pain at rest or on coughing at 24 h. [corrected]. Lidocaine reduced 24-h morphine consumption by a mean (95% CI) of 13.9 (2.2-25.7) mg, p = 0.021, from a mean (SD) of 52.3 (26.9) mg with saline. There were no differences in other outcomes.

Indexed as

Anesthetics, LocalLidocaineProstatectomyHumansInfusions, IntravenousLength of StayMaleMiddle AgedPerioperative CarePostoperative PainProstateTreatment OutcomeAnesthetics, LocalLidocaine

Identifiers

PMID26749026
PMCPMC4849200
OpenAlexW2225783489

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.