Evidence map›Paper›PMID 26748766›Full record

ArticleAddiction (Abingdon, England)2016

When psychopathology matters most: identifying sensitive periods when within-person changes in conduct, affective and anxiety problems are associated with male adolescent substance use.

Magdalena Cerdá, Seth J Prins, Sandro Galea, Chanelle J Howe, Dustin Pardini

Open access · greenAbstract read
In one paragraph

Article in Addiction (Abingdon, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 1 country.

Magdalena CerdáDepartment of Emergency Medicine, School of Medicine, University of California, Davis, CA, USA.
Seth J PrinsDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA.
Sandro GaleaBoston University School of Public Health, Boston, MA, USA.
Chanelle J HoweDepartment of Epidemiology, Brown University School of Public Health, Providence, RI, USA.
Dustin PardiniSchool of Criminology and Criminal Justice at Arizona State University, Phoenix, AZ, USA.
Arizona State University · USBoston University · USBrown University · USColumbia University · USUniversity of California, Davis · US

Funding

Mental Health and Service Utilization Among Reserve and National Guard ForcesR01MH082729 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GALEA, SANDRO · 2008 to 2012
$3.0M
TRACING DIVERGING LIVES AND CONVERGING PROBLEMSR01MH050778 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LOEBER, ROLF · 1993 to 2005
$2.2M
Trajectories of Substance Use and Comorbid Mental IllnessK01DA030449 · NIDA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CERDA, MAGDALENA · 2011 to 2015
$897k
Brain Function, Cognitive and Emotional Processing, and Behavioral DysregulationK01MH078039 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PARDINI, DUSTIN A · 2007 to 2011
$751k
Diverging Marijuana Use Trajectories in Black & White Men: Antecedents & OutcomesR01DA034608 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI STEPP, STEPHANIE D · 2013 to 2015
$667k
NIDA NIH HHS DA030449NIDA NIH HHS DA411018NIDA NIH HHS K01 DA030449NIDA NIH HHS R01 DA034608NIMH NIH HHS K01 MH078039NIMH NIH HHS MH078039NIMH NIH HHS MH 082729NIMH NIH HHS MH 48890NIMH NIH HHS MH 50778NIMH NIH HHS R01 MH050778NIMH NIH HHS R01 MH082729
6 · The paper itself

Abstract

BACKGROUND AND

aimsThere is a documented link between common psychiatric disorders and substance use in adolescent males. This study addressed two key questions: (1) is there a within-person association between an increase in psychiatric problems and an increase in substance use among adolescent males and (2) are there sensitive periods during male adolescence when such associations are more evident?

designAnalysis of longitudinal data collected annually on boys selected randomly from schools based on a comprehensive public school enrollment list from the Pittsburgh Board of Education.

settingRecruitment occurred in public schools in Pittsburgh, Pennsylvania, USA.

participantsA total of 503 boys assessed at ages 13-19 years, average cooperation rate = 92.1%. MEASUREMENTS: Diagnostic and Statistical Manual (DSM)-oriented affective, anxiety and conduct disorder problems were measured with items from the caregiver, teacher and youth version of the Achenbach scales. Scales were converted to t-scores using age- and gender-based national norms and combined by taking the average across informants. Alcohol and marijuana use were assessed semi-annually by a 16-item Substance Use Scale adapted from the National Youth Survey.

findingsWhen male adolescents experienced a 1-unit increase in their conduct problems t-score, their rate of marijuana use subsequently increased by 1.03 [95% confidence interval (CI) = 1.01, 1.05], and alcohol quantity increased by 1.01 (95% CI = 1.0002, 1.02). When adolescents experienced a 1-unit increase in their average quantity of alcohol use, their anxiety problems t-score subsequently increased by 0.12 (95% CI = 0.05, 0.19). These associations were strongest in early and late adolescence.

conclusionsWhen adolescent boys experience an increase in conduct disorder problems, they are more likely to exhibit a subsequent escalation in substance use. As adolescent boys increase their intensity of alcohol use, they become more likely to develop subsequent anxiety problems. Developmental turning points such as early and late adolescence appear to be particularly sensitive periods for boys to develop comorbid patterns of psychiatric problems and substance use.

Indexed as

AdolescentAge DistributionAnxiety DisordersConduct DisorderHumansLongitudinal StudiesMaleMood DisordersPennsylvaniaSubstance-Related DisordersYoung AdultAnxietycomorbidityconduct disorderdepressionsubstance use

Identifiers

PMID26748766
PMCPMC4826797
OpenAlexW2230424113

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.